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Serum Thioredoxin 1 Level Has Close Relation with Myocardial Damage Amount in Acute Myocardial Infarction Patients

Shim YK, Kim JT, Seong MH, Kim YJ, Shim TJ, Kim SM, Lee SY, Bae JW, Kim KS, Hwang KK, Kim DW, Cho MC

Thioredoxin-1 (Trx-1) is one of important anti-oxidative molecules to overcome the oxidative stress. The aim of the present study is to investigate the clinical relationship between serum concentration of Trx-1...
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Comparison of bare metal stent and paclitaxel-eluting stent using a novel rat aorta stent model

Kwon JS, Park RK, Shim TJ, Jeong MH, Cho MC, Ahn Y, Kim DW

The purpose of our study was to create a novel rat aorta stent implantation model. Stainless steel bare metal stents (BMS) or paclitaxel-eluting stents (PES) were implanted in male Sprague-Dawley...
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Perivascular Delivery of Rapamycin in Pluronic Gel Inhibits Neointimal Hyperplasia in a Rat Carotid Artery Injury Model, and the Complementary Role of Carotid Arteriography

Jung MJ, Kwon JS, Park NK, Kim YK, Shim TJ, Jeong IH, Bae JW, Hwang KK, Kim DW, Cho MC

BACKGROUND AND OBJECTIVES: Rapamycin has been shown to inhibit the vascular smooth muscle cell migration and proliferation that contributes to neointimal formation. We investigated whether the perivascular delivery of rapamycin...
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Establishment of a eNOS Gene Therapy Model Using PLGA Nanosphere in Spontaneous Hypertensive Rat

Shim TJ, Choi EJ, Park KJ, Kim YJ, Kim SJ, Lee SY, Kim SM, Bae JW, Hwang KK, Kim DW, Cho MC

  • KMID: 2012310
  • J Korean Soc Hypertens.
  • 2010 Jun;16(2):28-38.
BACKGROUND: Poly(lactic-co-glycolic acid) (PLGA) has been studied for many years as a suitable drug delivery material, because of its chemical biocompatibility, total biodegradability, and non-toxic degradation products. The aim of...
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