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VEGF-VEGFR Signals in Health and Disease

Shibuya M

  • KMID: 2048324
  • Biomol Ther.
  • 2014 Jan;22(1):1-9.
Vascular endothelial growth factor (VEGF)-VEGF receptor (VEGFR) system has been shown to play central roles not only in physiological angiogenesis, but also in pathological angiogenesis in diseases such as cancer....
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Methemoglobinemia caused by a low dose of prilocaine during general anesthesia

Shibuya M, Hojo T, Hase Y, Kimura Y, Fujisawa T

Methemoglobinemia is a blood disorder in which an abnormal amount of methemoglobin is produced, and prilocaine is one of the drugs that can cause this disorder. The maximum recommended dose...
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Prolongation of the effect of a single dose of rocuronium in a patient with postpolio syndrome under desflurane anesthesia: a case report

Kimura Y, Nitta Y, Shibuya M, Fujisawa T

Postpolio syndrome (PPS) is widely known to manifest as muscle weakness in patients affected by poliomyelitis in early childhood. This is caused by the long-term overwork of motor nerves regenerated...
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A Cohen syndrome patient whose muscle-relaxant effect may have been prolonged during general anesthesia: a case report

Ishikawa E, Shibuya M, Kimura Y, Kamekura N, Fujisawa T

Cohen syndrome is a rare genetic disorder associated with mutations in the VPS13B gene. Individuals with this disorder present with diverse clinical manifestations, including muscle hypotonia, intellectual disabilities, and typical...
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General anesthesia with a transcutaneous pacemaker for a Noonan syndrome patient with advanced atrioventricular block discovered in the remote period after open-heart surgery: a case report

Ishikawa E, Shibuya M, Yokoyama A, Hojo T, Kimura Y, Fujisawa T

We provided general anesthesia management to a patient with advanced atrioventricular block, which was discovered in the remote period after open-heart surgery. A 21-year-old man with Noonan syndrome was scheduled...
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Risk factors for postoperative nausea and vomiting in patients of orthognathic surgery according to the initial onset time: a cross-sectional study

Ishikawa E, Hojo T, Shibuya M, Teshirogi T, Hashimoto K, Kimura Y, Fujisawa T

Background: A high incidence (40–73%) of postoperative nausea and vomiting (PONV) has been reported following orthognathic surgery, and various risk factors have been associated with it. Identifying PONV risk factors...
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Does physiotherapy after rotator cuff repair require supervision by a physical therapist?: a meta-analysis

Karasuyama M, Gotoh M, Oike T, Nishie K, Shibuya M, Nakamura H, Ohzono H, Kawakami J

Background: A supervised physiotherapy program (SPP) is a standard regimen after surgical rotator cuff repair (RCR); however, the effect of a home-based exercise program (HEP), as an alternative, on postoperative...
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