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Targeting the Transforming Growth Factor-beta Signaling in Cancer Therapy

Sheen YY, Kim MJ, Park SA, Park SY, Nam JS

  • KMID: 2048301
  • Biomol Ther.
  • 2013 Sep;21(5):323-331.
TGF-beta pathway is being extensively evaluated as a potential therapeutic target. The transforming growth factor-beta (TGF-beta) signaling pathway has the dual role in both tumor suppression and tumor promotion. To...
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Anti-Cancer Effect of 3-(4-dimethylamino phenyl)-N-hydroxy-2-propenamide in MCF-7 Human Breast Cancer

Min KN, Joung KE, Kim DK, Sheen YY

  • KMID: 2380177
  • Environ Health Toxicol.
  • 2012 ;27(1):e2012010.
OBJECTIVES: In recent years, a number of structurally diverse Histone deacetylase (HDAC) inhibitors have been identified and these HDAC inhibitors induce growth arrest, differentiation and/or apoptosis of cancer cells in...
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