- Targeting Arginine-Dependent Cancers with Arginine-Degrading Enzymes: Opportunities and Challenges
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Phillips M, Sheaff MT, Szlosarek
- KMID: 2167635
- Cancer Res Treat.
- 2013 Dec;45(4):251-262.
Arginine deprivation is a novel antimetabolite strategy for the treatment of arginine-dependent cancers that exploits differential expression and regulation of key urea cycle enzymes. Several studies have focused on inactivation... -
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