- Cholera toxin mediated regulation of the expression of Gq alpha and G11 alpha GTP binding proteins
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Shah BH
- KMID: 1029937
- Exp Mol Med.
- 1999 Jun;31(2):89-94.
Previously it has been shown that persistent activation of the stimulatory adenylyl cyclase pathway with cholera toxin (CT) downregulates the Gs alpha polypeptide (80%) in a cAMP-independent manner in C6 glioma cells... -
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- Co-activation of Gi and Gq proteins exerts synergistic effect on human platelet aggregation through activation of phospholipase C and Ca2+ signalling pathways
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Shah BH, Siddiqui A, Qureshi KA, Khan M, Rafi S, Ujan VA, Yakoob MY, Rasheed H, Saeed SA
- KMID: 755026
- Exp Mol Med.
- 1999 Mar;31(1):42-46.
Our previous studies have shown that subthreshold concentrations of two platelet agonists exert synergistic effects on platelet aggregation. Here we studied the mechanism of synergistic interaction of 5-hydroxytryptamine (5-HT) and epinephrine mediated platelet... -
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- Molecular mechanisms involved in human platelet aggregation by synergistic interaction of platelet-activating factor and 5-hydroxytryptamine.
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Shah BH, Rasheed H, Rahman IH, Shariff AH, Khan FL, Rahman HB, Hanif S, Saeed SA
- KMID: 1457534
- Exp Mol Med.
- 2001 Dec;33(4):226-233.
Our recent studies have shown that co-activation of Gq and Gi proteins by 5-hydroxytryptamine (5-HT) and adrenaline show synergism in human platelet aggregation. This study was conducted to examine the... -
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