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Effects and Predictive Factors of Immunosuppressive Therapy Combined with Umbilical Cord Blood Infusion in Patients with Severe Aplastic Anemia

Zhang X, Li Z, Geng W, Song B, Wan C

PURPOSE: To investigate the efficacy and safety of umbilical cord blood (UCB) infusion (UCBI) plus immunosuppressive therapy (IST) treatment in comparison to IST treatment, as well as predictive factors for...
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Should we still use Camitta's criteria for severe aplastic anemia?

Yoon HH, Huh SJ, Lee JH, Lee S, Kim SH, Kwon HC, Kim HJ

BACKGROUND: The criteria by Camitta for diagnosis in severe aplastic anemia (SAA) has been used since 1976. However, there has been no attempt to verify the Camitta's criteria, that the...
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Long-term Clinical Outcome in Children with very Severe Aplastic Anemia

Lim JE, Lim CH, Lee JW, Jang PS, Chung NG, Cho B, Jeong DC, Kim HK

  • KMID: 2168963
  • Clin Pediatr Hematol Oncol.
  • 2008 Oct;15(2):92-100.
PURPOSE: We retrospectively investigated the long-term clinical outcome in children with very severe aplastic anemia (vSAA) for choice of management of them. METHODS: We reviewed and analyzed the medical records of...
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Outcome of Severe Aplastic Anemia Treated with Immunosuppressive Therapy Compared with Bone Marrow Transplantation

Kim HI, Baik SH, Yoo JH, Joe DY, Park JI, Lee HW, Kang SY, Jang JH, Park JS, Choi JH, Kim HC

BACKGROUND: The response rates and survival following allogeneic bone marrow transplantation (BMT) or immunosuppressive treatment were compared in severe aplastic anemia (SAA) and the prognostic factors related with survival identified. METHODS:...
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A Case of Invasive Maxillary and Orbital Aspergillosis Inhematopoietic Stem Cell Transplantation Recipient with Severe Aplastic Anemia

Joo YD, Lee WS, Kim JL, Yang JW, Kim HW, Park SK, Sohn CH

Invasive aspergillosis (IA) of the paranasal sinuses is a rare infectious complication associated with allogeneic hematopoietic stem cell transplantation (HSCT). However, immunocompromised patients are particularly at risk of fulminant IA....
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The Effects of Multiple Transfusion on the Outcomes of Bone Marrow Transplantation from HLA-matched Sibling Donor in Patients with Severe Aplastic Anemia

Bin JH, Yoo YK, Kim SY, Jang PS, Chung NG, Cho B, Jeong DC, Lee SJ, Kim HK

  • KMID: 2278260
  • Korean J Pediatr Hematol Oncol.
  • 2003 Apr;10(1):30-38.
PURPOSE: We investigated the effects of pretransplant-transfusion on engraftment, graft versus host disease (GVHD) and graft rejection after bone marrow transplantation (BMT) in children with severe aplastic anemia who had...
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Allogeneic Hematopoietic Stem Cell Transplantation Using Intensified Conditioning Regimen and High dose Stem Cells in Severe Aplastic Anemia

Park CY, Min WS, Shin HJ, Kim YJ, Park YH, Kim HJ, Lee S, Min CK, Kim DW, Lee JW, Park JW, Kim CC

  • KMID: 2083437
  • Korean J Hematol.
  • 2002 May;37(2):106-113.
BACKGROUND: Graft rejection as well as graft versus host disease is the main cause of failure after allogeneic hematopoietic stem cell transplantation (HSCT) in patient with severe aplastic anemia. Graft...
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The Management Of Patients With Severe Aplastic Anemia In Oral & Maxillofacial Surgery

Yoon HJ, Park JU

  • KMID: 2118284
  • J Korean Assoc Oral Maxillofac Surg.
  • 2001 Oct;27(5):464-467.
Aplastic anemia is a hematopoietic disorder characterized by marked reduction or absence of erythoid, granulocytic, and megakariocytic cells in the bone marrow with resultant pancytopenia. To control of infection &...
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Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia

Kim I, Lee DH, Bang SM, Byun JH, Chang HM, Lee MH, Yoo YJ, Ahn JS, Lee JT, Im SA, Jung CW, Yang SH, Lee HB, Suh C, Oh MD, Choe KW, Han KS, Park MH, Kim IH, Ha SW, Park CI, Jung KH, Park S, Kim BK

  • KMID: 2143341
  • Korean J Hematol.
  • 2000 Nov;35(3-4):195-205.
BACKGROUND: The outcome of hematopoietic stem cell transplantation (HSCT) for patients with severe aplastic anemia (SAA) in Seoul National University Hospital was analyzed retrospectively. METHODS: Between January, 1990 and March, 1999,...
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Comparison of Combined Immune Suppression, Bone Marrow Transplantation and Androgen Treatment in Childhood Severe Aplastic Anemia

Hwang MJ, Kook H, Kim CJ, Park HJ, Kim SY, Park A, Hwang TJ

  • KMID: 1535331
  • Korean J Pediatr Hematol Oncol.
  • 1998 Oct;5(2):266-277.
PURPOSE: The purpose of this study is to compare treatment response and survival according to treatment modalities, such as allogeneic bone marrow transplantation (BMT), combined immunosuppression and supportive care, and...
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Effect of Desferrioxamine Therapy in Patients with Transfusional Hemosiderosis Due to Severe Aplastic Anemia

Lee JH, Cho B, Jeong DC, Kim HK

  • KMID: 2072455
  • Korean J Pediatr Hematol Oncol.
  • 1997 Apr;4(1):62-69.
BACKGROUND: This study was carried out to evaluate the efficacy of desferrioxamine as a chelating agent in iron overloaded patients with severe aplastic anemia due to multiple transfusion. METHODS AND MATERIALS:...
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Allogeneic Bone Marrow Transplantation Experience for Children with Severe Aplastic Anemia and Refractory Leukemia

Jeong DC, Kim HK

  • KMID: 2335165
  • J Korean Pediatr Soc.
  • 1996 Jan;39(1):97-105.
PURPOSE: We reviewed the result of allogeneic bone marrow transplantation(BMT) from HLA-identical sibling donors in children with refractory stem cell disorder along with future implication. METHODS: Forty-two children with refractory...
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Treatment of severe aplastic anemia: comparison between bone marrow transplantation and immunomodulation

Jeong DC, Choi SD, Choi WG, Kim HK, Lee KS, Lee DB

  • KMID: 1691900
  • J Korean Pediatr Soc.
  • 1991 Feb;34(2):172-179.
No abstract available.
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Therapy of severe aplastic anemia with anti-human thymocyte globulin (ATGAM) with and without HLA-haploidentical bone-marrow infusion

Kim KY

Six patients with severe aplastic anemia treated with horse anti-human thymocyte globulin (ATG) and androgen. Four of these patients were only given ATG (ATGAMR), 16 mg/Kg/dose x 10 doses. The...
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