- Multi-phenotypic Role of Serum Response Factor in the Gastrointestinal System
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Ro S
- KMID: 2203569
- J Neurogastroenterol Motil.
- 2016 Apr;22(2):193-200.
- doi: 10.5056/jnm15183
Serum response factor (SRF) is a master transcription factor of the actin cytoskeleton that binds to highly conserved CArG boxes located within the majority of smooth muscle cell (SMC)-restricted promoters/enhancers.... -
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- Expression and Prognostic Significance of Serum Response Factor in Cholangiocarcinoma
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Park SY, Jang KY, Kim YN, Kim HJ, Park HS, Chung MJ, Yu HC, Cho BH, Kim KR, Moon WS
- KMID: 1472636
- Korean J Pathol.
- 2009 Dec;43(6):517-522.
- doi: 10.4132/KoreanJPathol.2009.43.6.517
BACKGROUND: Serum response factor (SRF) is a transcriptional factor that plays an important role in cell growth and differentiation for several types of cells. The expression of SRF in cholangiocarcinoma... -
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- Serum Response Factor Is Essential for Prenatal Gastrointestinal Smooth Muscle Development and Maintenance of Differentiated Phenotype
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Park C, Lee MY, Park PJ, Ha SE, Berent RM, Fuchs R, Miano JM, Becker LS, Sanders KM, Ro S
- KMID: 2381308
- J Neurogastroenterol Motil.
- 2015 Oct;21(4):589-602.
- doi: 10.5056/jnm15063
BACKGROUND/AIMS: Smooth muscle cells (SMCs) characteristically express serum response factor (SRF), which regulates their development. The role of SRF in SMC plasticity in the pathophysiological conditions of gastrointestinal (GI) tract... -
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- Suppression of the ERK–SRF axis facilitates somatic cell reprogramming
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Huh S, Song HR, Jeong GR, Jang H, Seo NH, Lee JH, Yi JY, Lee B, Choi HW, Do JT, Kim JS, Lee SH, Jung JW, Lee T, Shim J, Han MK, Lee TH
- KMID: 2440030
- Exp Mol Med.
- 2018 Feb;50(2):e448.
- doi: 10.1038/emm.2017.279
The molecular mechanism underlying the initiation of somatic cell reprogramming into induced pluripotent stem cells (iPSCs) has not been well described. Thus, we generated single-cell-derived clones by using a combination... -
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