- 5-HT1A Partial Agonist Tandospirone for Behavioral and Psychological Symptoms in Oldest-old Patients with Dementia at a Special Elderly Nursing Home
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Ochi S, Mori T, Iga Ji, Ueno Si
- KMID: 2519559
- Clin Psychopharmacol Neurosci.
- 2021 Aug;19(3):514-520.
- doi: 10.9758/cpn.2021.19.3.514
Objective: To investigate the efficacy of tandospirone, an azapirone anxiolytic similar to buspirone that is used in Japan, for behavioral and psychological symptoms of dementia (BPSD), especially in oldest-old patients. Methods:... -
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- The Role of Serotonin in Ventricular Repolarization in Pregnant Mice
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Cui S, Park H, Park H, Mun D, Lee SH, Kim H, Yun N, Kim H, Kim M, Pak HN, Lee MH, Joung B
- KMID: 2418792
- Yonsei Med J.
- 2018 Mar;59(2):279-286.
- doi: 10.3349/ymj.2018.59.2.279
PURPOSE: The mechanisms underlying repolarization abnormalities during pregnancy are not fully understood. Although maternal serotonin (5-hydroxytryptamine, 5-HT) production is an important determinant for normal fetal development in mice, its role... -
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- Glucosylsphingosine Activates Serotonin Receptor 2a and 2b: Implication of a Novel Itch Signaling Pathway
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Afzal R, Shim WS
- KMID: 2389381
- Biomol Ther.
- 2017 Sep;25(5):497-503.
- doi: 10.4062/biomolther.2016.207
Recent reports claimed that glucosylsphingosine (GS) is highly accumulated and specifically evoking itch-scratch responses in the skins of atopic dermatitis (AD) patients. However, it was unclear how GS can trigger... -
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- Ondansetron Inhibits Voltage-Gated K⺠Current of Ventricular Myocytes from Pregnant Mouse
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Cui S, Park H, Park H, Mun D, Kim HE, Yun N, Joung B
- KMID: 2387536
- Int J Arrhythm.
- 2017 Jun;18(2):77-84.
- doi: 10.18501/arrhythmia.2017.012
BACKGROUND: The Htr3a antagonist, ondansetron, has been reported to prolong the QT interval and induce Torsades de pointes in the treatment of postoperative nausea and vomiting. To explore the mechanisms... -
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- Ketanserin and Naftopidil Enhance the Potentiating Effect of Alpha-Methyl-Serotonin on the Neurally-Induced Contraction of Human Isolated Urinary Bladder Muscle Strips
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Hattori T, Lluel P, Rouget C, Rekik M, Yoshiyama
- KMID: 2375590
- Int Neurourol J.
- 2017 Mar;21(1):20-28.
- doi: 10.5213/inj.1732758.379
PURPOSE: The aim of this study was to assess the potential involvement of a specific subtype of 5-hydroxytryptamine (5-HT), 5HT(2) receptors in neurally-induced contractions of the human detrusor. METHODS: Contractile responses... -
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- Associations between Serotonergic Genes and Escitalopram Treatment Responses in Patients with Depressive Disorder and Acute Coronary Syndrome: The EsDEPACS Study
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Kang HJ, Bae KY, Kim SW, Shin IS, Hong YJ, Ahn Y, Jeong MH, Park SW, Kim YH, Yoon JS, Kim JM
- KMID: 2316609
- Psychiatry Investig.
- 2016 Jan;13(1):157-160.
- doi: 10.4306/pi.2016.13.1.157
Genes related to serotonin are associated with responses to treatment for depression. We examined associations between the serotonin transporter (5-HTT) and serotonin 2a receptor (5-HTR2a) genes and responses to treatment... -
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- Antiallodynic effects of intrathecal tianeptine in a neuropathic pain rat
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Lin H, Lee HG, Yoon MH
- KMID: 1797467
- Anesth Pain Med.
- 2014 Apr;9(2):93-97.
BACKGROUND: Tianeptine is an antidepressant drug which is used for treating depression. Interestingly, the tianeptine has shown antinociceptive effects within a variety of nociceptions. The aim of this study is... -
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- Effects of Genetic and Environmental Factors on the Depression in Early Adulthood
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Kim SK, Lee SI, Shin CJ, Son JW, Eom SY, Kim H
- KMID: 1770031
- Korean J Biol Psychiatry.
- 2008 Feb;15(1):14-22.
OBJECTIVES: The authors purposed to present data for explaining gene-environmental interaction causing depressive disorder by examining the effects of genetic factors related to the serotonin system and environmental factors such... -
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- Association Study between 5-HT2A Receptor and DRD3 Receptor Gene Polymorphism and Clinical Response to Atypical Antipsychotics in Patients with Schizophrenia
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Kim BS, Joo YH, Kim CY, Park JH, Song KY, Han OS
- KMID: 2340671
- J Korean Neuropsychiatr Assoc.
- 2002 May;41(3):409-420.
OBJECTIVES: This study was performed based on the hypothesis that the interindividual differences in clinical response to atypical antipsychotics might be associated with serotonin 2A receptor(5-HT2A) gene and(or) dopamine D3... -
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- Serotonin in Psychiatry
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Yang BH
- KMID: 2202975
- J Korean Soc Biol Psychiatry.
- 1997 Nov;4(2):155-161.
Serotonin has been implicated in the etiology of many disease states and may be particularly mental illness, such as depression, anxiety, schizophrenia, sleep disorders, suicide, eating disorders, obsessive compulsive disorders,... -
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- Distribution of Serotonin-2 Receptor in the Superior Collicullus of the Adult Rat: A Radioarutographic Study
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Lee NK, Kim MH, Ahn CB
- KMID: 2123146
- J Korean Ophthalmol Soc.
- 1993 Dec;34(12):1262-1268.
The superior colliculus is a laminated structure that consisted with superficial and deep layers in the roof of midbrain and the center of visual information and sensorimotor intergration. The deep... -
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