- Serotonin Reuptake Inhibitor Increases Pseudarthrosis Rates in Anterior Cervical Discectomy and Fusions
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Lambrechts MJ, D'Antonio N, Toci G, Karamian B, Pezzulo J, Farronato D, Canseco J, Kaye ID, Woods B, Rihn J, Kurd M, Lee J, Hilibrand A, Kepler C, Vaccaro AR, Schroeder G
- KMID: 2541658
- Asian Spine J.
- 2023 Apr;17(2):304-312.
- doi: 10.31616/asj.2022.0065
Study Design: Retrospective cohort. Purpose: To determine (1) the effects of serotonin reuptake inhibitors in pseudarthrosis rates after anterior cervical decompression and fusion (ACDF) and (2) to identify patient-reported outcome measures... -
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- Retrospective analysis of the incidence and predictors of postoperative nausea and vomiting after orthopedic surgery under spinal anesthesia
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Ju JW, Kwon J, Yoo S, Lee HJ
- KMID: 2540999
- Korean J Anesthesiol.
- 2023 Apr;76(2):99-106.
- doi: 10.4097/kja.22237
Background: Postoperative nausea and vomiting (PONV) commonly occurs after spinal anesthesia; however, its incidence rate and predictors have been scarcely studied. Therefore, we aimed to investigate its incidence rate and... -
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- Imbalance in the spinal serotonergic pathway induces aggravation of mechanical allodynia and microglial activation in carrageenan inflammation
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Jin J, Kang DH, Jeon J, Lee HG, Kim WM, Yoon MH, Choi JI
- KMID: 2537612
- Korean J Pain.
- 2023 Jan;36(1):51-59.
- doi: 10.3344/kjp.22297
Background: This study investigated the effect of an excess and a deficit of spinal 5-hydroxytryptamine (5-HT) on the mechanical allodynia and neuroglia activation in a rodent pain model of carrageenan... -
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- Current Prescription Status of Contraindicated Drug Combinations Causing Serotonin Syndrome: Analysis of HIRA-NPS Data
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Ryu JG, Kim SY, Park S, Je NK
- KMID: 2537781
- Korean J Clin Pharm.
- 2022 Dec;32(4):313-320.
- doi: 10.24304/kjcp.2022.32.4.313
Background: Serotonin syndrome is a life-threatening disease if not appropriately treated. This study aimed to investigate the prescription status of contraindicated drug combinations that cause serotonin syndrome and identify the... -
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- Anti‑stress effects of Fameyes in in vitro and in vivo models of stresses
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Hong J, Lee T, Kim I, Lee S, Jeon B, Lee J, Won M, Kim S
- KMID: 2537637
- Lab Anim Res.
- 2022 Dec;38(4):337-344.
- doi: 10.1186/s42826-022-00149-w
Background: Fameyes (a mixture of Clematis mandshurica Rupr. extract (CMRE) and Erigeron annuus (L.) Pers. extract (EAPE)) containing scutellarin and chlorogenic acid as major components has been reported to relieve... -
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- Confounding by Indication in Studies of Selective Serotonin Reuptake Inhibitors
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Lee J, Chang SM
- KMID: 2536194
- Psychiatry Investig.
- 2022 Nov;19(11):873-883.
- doi: 10.30773/pi.2022.0209
Selective serotonin reuptake inhibitors (SSRIs) are used worldwide as the first-line pharmacological treatment for depression. Although SSRI use can increase the risk of suicide, fractures, and infertility, the nature of... -
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- Anger, a Result and Cause of Stroke: A Narrative Review
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Choi-Kwon S, Kim JS
- KMID: 2534260
- J Stroke.
- 2022 Sep;24(3):311-322.
- doi: 10.5853/jos.2022.02516
Post-stroke mood and emotional disturbances are frequent and diverse in their manifestations. Among them, post-stroke depression is the best known. Although post-stroke anger (PSA) has been studied relatively less, it... -
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- Selective Serotonin Reuptake Inhibitor Promotes Bone-Tendon Interface Healing in a Rotator Cuff Tear Rat Model
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Yoon JP, Yoon JW, Kim HM, Oh JH
- KMID: 2533920
- Tissue Eng Regen Med.
- 2022 Aug;19(4):853-860.
- doi: 10.1007/s13770-022-00444-6
BACKGROUND: Selective serotonin reuptake inhibitor (SSRI) is believed to accelerate wound healing, and thus expected to have a positive effect on rotator cuff repair. We hypothesized that SSRI has a... -
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- Peroxiredoxin 6 Overexpression Induces Anxiolytic and Depression-Like Behaviors by Regulating the Serotonergic Pathway in Mice
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Gu SM, Yu E, Kim YE, Yoon SS, Lee D, Hong JT, Yun J
- KMID: 2530998
- Biomol Ther.
- 2022 Jul;30(4):334-339.
- doi: 10.4062/biomolther.2021.169
Peroxiredoxin 6 (PRDX6) is a bifunctional protein with both glutathione peroxidase and calcium-independent phospholipase activity. Recently, we reported that PRDX6 plays an important role in dopaminergic neurodegeneration in Parkinson’s disease. However,... -
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- Prokinetic Agents
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Song HY, Jung SW, Kim YS
- KMID: 2530634
- Korean J Helicobacter Up Gastrointest Res.
- 2022 Jun;22(2):86-101.
- doi: 10.7704/kjhugr.2022.0011
Gastrointestinal (GI) prokinetic agents are drugs that increase GI motility and promote the movement of contents in the GI tract by amplifying and controlling the contraction of GI smooth muscle.... -
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- Serotonin Modulates the Correlations between Obsessive-compulsive Trait and Heart Rate Variability in Normal Healthy Subjects: A SPECT Study with [ 123 I]ADAM and Heart Rate Variability Measurement
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Kuo CY, Chen KC, Lee IH, Tseng HH, Chiu NT, Chen PS, Yang YK, Chang WH
- KMID: 2530462
- Clin Psychopharmacol Neurosci.
- 2022 May;20(2):271-278.
- doi: 10.9758/cpn.2022.20.2.271
Objective: The impact of serotonergic system on obsessive-compulsive disorder (OCD) is well studied. However, the correlation between OC presentations and autonomic nervous system (ANS) is still unclear. Furthermore, whether the... -
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- Associations of Serum Serotonin Levels with 12-week and 12-month Remission in Patients with Depressive Disorders
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Choi W, Kang HJ, Kim JW, Kim HK, Kang HC, Lee JY, Kim SW, Stewart R, Kim JM
- KMID: 2530460
- Clin Psychopharmacol Neurosci.
- 2022 May;20(2):248-258.
- doi: 10.9758/cpn.2022.20.2.248
Objective: To investigate associations between baseline serum serotonin levels and short- and long-term treatment outcomes in outpatients with depressive disorders in a naturalistic one-year prospective study design. Methods: Patients were recruited... -
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- Selective Serotonin Re-Uptake Inhibitors for Premature Ejaculation in Adult Men: A Cochrane Systematic Review
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Sathianathen NJ, Hwang EC, Mian R, Bodie JA, Soubra A, Lyon JA, Sultan S, Dahm P
- KMID: 2527323
- World J Mens Health.
- 2022 Apr;40(2):257-263.
- doi: 10.5534/wjmh.210155
Purpose: Selective serotonin re-uptake inhibitors (SSRIs) are frequently used to treat premature ejaculation (PE) in men. We performed a Cochrane review to assess the efficacy of SSRI treatment for PE. Materials... -
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- Pharmacotherapy for late-life depression
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Han KM
- KMID: 2527358
- J Korean Med Assoc.
- 2022 Mar;65(3):176-184.
- doi: 10.5124/jkma.2022.65.3.176
Background: Late-life depression (LLD) is one of the most common psychiatric disorders. However, LLD is often undetected or inadequately treated by clinicians. This review summarizes the recent research on pharmacotherapy... -
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- Comparison of Bleeding Tendency Between Selective Serotonin Reuptake Inhibitors and Serotonin Norepinephrine Reuptake Inhibitors Using Platelet Function Analyzer
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Koo SM, Kim H, Lee KJ
- KMID: 2524296
- Korean J Psychosom Med.
- 2021 Dec;29(2):153-161.
- doi: 10.22722/KJPM.2021.29.2.153
Objectives：The purpose of this study is to compare bleeding tendency of selective serotonin reuptake inhibitor (SSRI) and serotonin norepinephrine reuptake inhibitors (SNRI) using platelet function analyzer (PFA-100) in patients with... -
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- Serotonergic Regulation of Hepatic Energy Metabolism
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Park J, Jeong W, Yun C, Kim H, Oh CM
- KMID: 2523484
- Endocrinol Metab.
- 2021 Dec;36(6):1151-1160.
- doi: 10.3803/EnM.2021.1331
The liver is a vital organ that regulates systemic energy metabolism and many physiological functions. Nonalcoholic fatty liver disease (NAFLD) is the commonest cause of chronic liver disease and end-stage... -
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- Trazodone Add-on in COVID-19-related Selective Serotonin Reuptake Inhibitor-resistant Post-traumatic Stress Disorder in Healthcare Workers: Two Case Reports
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Berardis DD, Fornaro M, Ventriglio A, Valchera A, Vellante F, Pettorruso M, Martinotti G, Fraticelli S, Giannantonio MD
- KMID: 2522992
- Clin Psychopharmacol Neurosci.
- 2021 Nov;19(4):780-785.
- doi: 10.9758/cpn.2021.19.4.780
COVID-19 represents a significant stress factor for all people worldwide due to several factors, including quarantine, lockdowns, fear of contagion, deaths, and other traumatic events. However, the healthcare workers (HCWs)... -
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- Liberation of Serotonin Is Not Unaffected by Acetylcholine in Rat Hippocampus
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Kim JH, Ahn YS, Song YS
- KMID: 2522750
- Int Neurourol J.
- 2021 Nov;25(Suppl 2):S114-119.
- doi: 10.5213/inj.2142350.175
Purpose: Raised cerebral titers of acetylcholine have notable links with storage symptomatology related to lower urinary tract symptoms. The hippocampus contributes to the normal control of continence in the majority... -
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- Serotonin Discharge Regulation by Additional Neurotransmitters of Rat Hippocampus Associated With the Continence Central Circuit
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Kim JH, Ahn YS, Song YS
- KMID: 2522749
- Int Neurourol J.
- 2021 Nov;25(Suppl 2):S106-113.
- doi: 10.5213/inj.2142348.174
Purpose: The lower urinary tract is believed to be centrally regulated with the involvement of a range of neurotransmitters. The parasympathetic excitatory input to the urinary bladder is suppressed when... -
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- Serotonin syndrome in a patient with chronic pain taking analgesic drugs mistaken for psychogenic nonepileptic seizure: a case report
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Boudier-Revéret M, Chang MC
- KMID: 2521719
- Yeungnam Univ J Med.
- 2021 Oct;38(4):371-373.
- doi: 10.12701/yujm.2021.00948
Serotonin syndrome (SS) is a potentially life-threatening condition that is caused by the administration of drugs that increase serotonergic activity in the central nervous system. We report a case of... -
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