- In silico Screening of Chemical Libraries to Develop Inhibitors That Hamper the Interaction of PCSK9 with the LDL Receptor
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Min DK, Lee HS, Lee N, Lee CJ, Song HJ, Yang GE, Yoon D, Park SW
- KMID: 2163616
- Yonsei Med J.
- 2015 Sep;56(5):1251-1257.
- doi: 10.3349/ymj.2015.56.5.1251
PURPOSE: Proprotein convertase subtilisin/kexin type 9 (PCSK9) binds to the low density lipoprotein receptor (LDLR) and promotes degradation of the LDLR. Inhibition of PCSK9 either by reducing its expression or... -
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- Granzyme B and TIA-1 Expression in Chronic and Acute on Chronic Renal Allograft Rejection
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Hong SW, Jeong HJ, Kim SI, Moon JI, Kim YS, Park K
- KMID: 720623
- Yonsei Med J.
- 2001 Jun;42(3):285-290.
- doi: 10.3349/ymj.2001.42.3.285
Although active inflammation may be deleterious and indicate immunologic activation in chronically rejected grafts, the underlying mechanism of tissue destruction has been little studied. Twenty-four cases of chronic rejection (CR)... -
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