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The homotrimeric structure of HtrA2 is indispensable for executing its serine protease activity

Nam MK, Seong YM, Park HJ, Choi JY, Kang S, Rhim H

  • KMID: 1105275
  • Exp Mol Med.
  • 2006 Feb;38(1):36-43.
Serine protease activity of high temperature requrement 2 (HtrA2) is essential for promoting cell death, as well as for protecting against cellular stresses. An X-ray crystallographic study described the formation...
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