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Expression of Thymidylate Synthase in Gastric Cancer

Ko DG, Park CH, Ha DW, Seou HC, Kim DH

  • KMID: 2209325
  • J Korean Surg Soc.
  • 2000 Dec;59(6):738-745.
PURPOSE: 5-fluorouracil is one of the widely used chemotherapeutic agent whose metabolic product forms tight covalent binding complex with thymidylate synthase (TS) and thereby blocks the DNA synthesis process. Expression...
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