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New and improved influenza vaccine

Seong BL

No abstract available.
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Toward a universal influenza vaccine: from the perspective of protective efficacy

Jang YH, Seong BL

No abstract available.
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Control of Influenza:Development of Live Vaccine

Lee KH, Seo SU, Song JM, Ha SH, Kim HA, Lee JM, Seong BL

  • KMID: 1515467
  • Infect Chemother.
  • 2004 May;36(Suppl 1):S10-S13.
Although trivalent subunit vaccine has been available, the influenza vaccine has been under-utilized because of cumbersome route of vaccination and low level of protection. Therefore, there has always been a...
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Control of Avian Influenza: Calls for International Collaboration

Seong BL, Jung EJ

  • KMID: 2303879
  • Korean J Epidemiol.
  • 2006 Jun;28(1):36-40.
The 1918 "Spanish Flu", cause of the largest causality rate ever recorded in human history with 50 million deaths, is genetically related to the current H5N1 virus, suggesting the potential...
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Cross-Protective Immune Responses Elicited by Live Attenuated Influenza Vaccines

Jang YH, Seong BL

The desired effect of vaccination is to elicit protective immune responses against infection with pathogenic agents. An inactivated influenza vaccine is able to induce the neutralizing antibodies directed primarily against...
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Principles underlying rational design of live attenuated influenza vaccines

Jang YH, Seong BL

Despite recent innovative advances in molecular virology and the developments of vaccines, influenza virus remains a serious burden for human health. Vaccination has been considered a primary countermeasure for prevention...
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Reverse genetic platform for inactivated and live-attenuated influenza vaccine

Jung EJ, Lee KH, Seong BL

Influenza vaccine strains have been traditionally developed by annual reassortment between vaccine donor strain and the epidemic virulent strains. The classical method requires screening and genotyping of the vaccine strain...
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Recombinant influenza viruses as delivery vectors for hepatis B virus epitopes

Song JM, Lee KH, Seong BL

PURPOSE: Neuraminidase (NA) of influenza virus contains stalk region that shows a great deal of variability in both amino acid sequence and length. In this paper, we investigated generation of...
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Detection and Quantification of Residual Cellular DNA in the Production of Recombinant HPV-16 L1 Virus-Like Particles

Son HK, Jeong HS, Kim YL, Kim SN, Shin JH, Min HK, Seong BL, Park SN

A number of recombinant proteins isolated from cell sources are being produced for biopharmaceuticals. Although most biopharmaceuticals are highly purified, there is a safety concern that such recombinant products could...
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