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Cho KH, Kim MK, Kim TS, Kim BC, Lee SH, Hwang IY, Kim JT, Kim JK
KMID: 1807460
Chonnam Med J.
2000 Jun;36(2):179-185.
Selegiline HCl (MAO-B(R)) is a levorotatory acetylenic derivative of phenethylamine. The drug is an enzyme-activated irreversible inhibitor of monoamine oxidase (MAO), also known as mechanism-based, kcat, or "suicide" inhibitor. We...
Monoamine oxidase inhibitors (MAO-I) belong to the earliest drugs tried in Parkinson's disease (PD). They have been used with or without levodopa (L-DOPA). Non-selective MAO-I due to their side-effect/adverse reaction...
Mitochondrial permeability transition has been shown to be involved in neuronal cell death. Mitochondrial monoamine oxidase (MAO)-B is considered to play a part in the progress of nigrostriatal cell death....
OBJECTIVES: The present subacute study was designed to evaluate the effect of coenzyme Q 10 (CoQ10) in the 28 days aroclor 1254 exposure induced oxidative stress in mice brain.
METHODS: Biochemical...
Monoamine oxidase inhibitors (MAOI) have been widely used as antidepressants. Recently, there has been renewed interest in MAO inhibitors. The activity-guided fractionation of extracts from Angelica keiskei Koidzumi (A. keiskei...