- Multiple Group Testing Procedures for Analysis of High-Dimensional Genomic Data
-
Ko H, Kim K, Sun H
- KMID: 2366435
- Genomics Inform.
- 2016 Dec;14(4):187-195.
- doi: 10.5808/GI.2016.14.4.187
In genetic association studies with high-dimensional genomic data, multiple group testing procedures are often required in order to identify disease/trait-related genes or genetic regions, where multiple genetic sites or variants... -
- CITED
-
- Close
- SHARE
-
- Close
- Identification and Characterization of Human Genes Targeted by Natural Selection
-
Ryu HJ, Kim YJ, Park YK, Kim JJ, Park MY, Seo EJ, Yoo HW, Park IS, Oh B, Lee JK
- KMID: 2166417
- Genomics Inform.
- 2008 Dec;6(4):173-180.
The human genome has evolved as a consequence of evolutionary forces, such as natural selection. In this study, we investigated natural selection on the human genes by comparing the numbers... -
- CITED
-
- Close
- SHARE
-
- Close
- Genetic Diversity and Natural Selection in 42 kDa Region of Plasmodium vivax Merozoite Surface Protein-1 from China-Myanmar Endemic Border
-
Zhou X, Tambo E, Su J, Fang Q, Ruan W, Chen JH, Yin MB, Zhou XN
- KMID: 2395751
- Korean J Parasitol.
- 2017 Oct;55(5):473-480.
- doi: 10.3347/kjp.2017.55.5.473
Plasmodium vivax merozoite surface protein-1 (PvMSP1) gene codes for a major malaria vaccine candidate antigen. However, its polymorphic nature represents an obstacle to the design of a protective vaccine. In... -
- CITED
-
- Close
- SHARE
-
- Close
- Low Levels of Polymorphisms and Negative Selection in Plasmodum knowlesi Merozoite Surface Protein 8 in Malaysian Isolates
-
Ahmed MA, Kang HJ, Quan FS
- KMID: 2459485
- Korean J Parasitol.
- 2019 Aug;57(4):445-450.
- doi: 10.3347/kjp.2019.57.4.445
Human infections due to the monkey malaria parasite Plasmodium knowlesi is increasingly being reported from most Southeast Asian countries specifically Malaysia. The parasite causes severe and fatal malaria thus there... -
- CITED
-
- Close
- SHARE
-
- Close
- Identifying Copy Number Variants under Selection in Geographically Structured Populations Based on F-statistics
-
Song HH, Hu HJ, Seok IH, Chung YJ
- KMID: 2166489
- Genomics Inform.
- 2012 Jun;10(2):81-87.
- doi: 10.5808/GI.2012.10.2.81
Large-scale copy number variants (CNVs) in the human provide the raw material for delineating population differences, as natural selection may have affected at least some of the CNVs thus far... -
- CITED
-
- Close
- SHARE
-
- Close
- Editor's Introduction to This Issue (G&I 16:1, 2018)
-
Kim JI
- KMID: 2413244
- Genomics Inform.
- 2018 Mar;16(1):1-1.
- doi: 10.5808/GI.2018.16.1.1
No abstract available. -
- CITED
-
- Close
- SHARE
-
- Close
- Neuro-Humanities: The Recent Discourses on Memory and Cognition
-
Kwon T
- KMID: 1430640
- Psychoanalysis.
- 2013 Apr;24(1):29-38.
Investigating the human psyche in the field of natural science, William James and Sigmund Freud approached the human mind from a neuroscientific perspective. Even though the aim of each of... -
- CITED
-
- Close
- SHARE
-
- Close
- Synonymous Codon Usage Controls Various Molecular Aspects
-
Im EH, Choi SS
- KMID: 2404048
- Genomics Inform.
- 2017 Dec;15(4):123-127.
- doi: 10.5808/GI.2017.15.4.123
Synonymous sites are generally considered to be functionally neutral. However, there are recent contradictory findings suggesting that synonymous alleles might have functional roles in various molecular aspects. For instance, a... -
- CITED
-
- Close
- SHARE
-
- Close
- Evolutionary Hypotheses of Mental Disorder and Their Limitations
-
Park H
- KMID: 2465997
- J Korean Soc Biol Ther Psychiatry.
- 2019 Oct;25(3):165-182.
- doi: 10.0000/jksbtp.2019.25.3.165
Like the body of Hominin, mind is the result of natural selection. Therefore, an evolutionary approach in the biological aspects is essential for an intrinsic understanding of mental disorders. However,... -
- CITED
-
- Close
- SHARE
-
- Close
- Conversion of a murine monoclonal antibody A13 targeting epidermal growth factor receptor to a human monoclonal antibody by guided selection
-
Chang KH, Kim MS, Hong GW, Shin YN, Kim SH
- KMID: 1120142
- Exp Mol Med.
- 2012 Jan;44(1):52-59.
- doi: 10.3858/emm.2012.44.1.005
Epidermal growth factor receptor (EGFR) is an attractive target for tumor therapy because it is overexpressed in the majority of solid tumors and the increase in receptor expression levels has... -
- CITED
-
- Close
- SHARE
-
- Close
- The Connection between Charles Darwin's Evolutionary Theory of ‘Heredity of Behaviors’ and the 19th Century Neuroscience: The Influence of Neuroscience on Darwin's Overcoming of Lamarck's Theory of Evolution
-
Han S
- KMID: 2449181
- Korean J Med Hist.
- 2019 Apr;28(1):291-350.
- doi: 10.13081/kjmh.2019.28.291
The nineteenth century neuroscience studied the instinct of animal to understand the human mind. In particular, it has been found that the inheritance of unconscious behavior like instinct is mediated... -
- CITED
-
- Close
- SHARE
-
- Close
