- Neuroprotective effect of lithium after pilocarpine-induced status epilepticus in mice
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Hong N, Choi YS, Kim SY, Kim HJ
- KMID: 2371076
- Korean J Physiol Pharmacol.
- 2017 Jan;21(1):125-131.
- doi: 10.4196/kjpp.2017.21.1.125
Status epilepticus is the most common serious neurological condition triggered by abnormal electrical activity, leading to severe and widespread cell loss in the brain. Lithium has been one of the... -
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- Influence of Aspirin on Pilocarpine-Induced Epilepsy in Mice
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Jeong KH, Kim JY, Choi YS, Lee MY, Kim SY
- KMID: 1432758
- Korean J Physiol Pharmacol.
- 2013 Feb;17(1):15-21.
- doi: 10.4196/kjpp.2013.17.1.15
Aspirin (acetylsalicylic acid) is one of the most widely used therapeutic agents based on its pharmacological actions, including anti-inflammatory, analgesic, anti-pyretic, and anti-thrombotic effects. In this study, we investigated the... -
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- Effect of beta-Hydroxybutyrate on Flurothyl-Induced Seizure Susceptibility
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Shin CG, Kim DW
- KMID: 2176827
- J Korean Child Neurol Soc.
- 2010 Nov;18(2):225-229.
PURPOSE: The ketogenic diet (KD) remains a therapy in search of explanation although it is an established treatment for patients with intractable seizures. It was designed to mimic the biochemical... -
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- Increased Seizure Susceptibility and Up-regulation of nNOS Expression in Hippocampus Following Recurrent Early-life Seizures in Rats
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Kim DK
- KMID: 2150871
- J Korean Med Sci.
- 2010 Jun;25(6):905-911.
- doi: 10.3346/jkms.2010.25.6.905
This study aimed to determine the long-term change of seizure susceptibility and the role of nNOS on brain development following recurrent early-life seizures in rats. Video-EEG recordings were conducted between... -
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- The Protective Effect of Chlorpromazine on Flurothyl-Induced Seizure
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Kim DW
- KMID: 2007390
- J Korean Child Neurol Soc.
- 2003 Nov;11(2):234-237.
PURPOSE: Chlorpromazine(CPZ) is known to inhibit glutamate ehydrogenase(GDH). Reductive amination of alpha-ketoglutarate is catalyzed by GDH and forms glutamate, a major excitatory neurotransmitter. Thus, I hypothesized that CPZ might have... -
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- Effect of the Ketogenic Diet on Flurothyl-Induced Seizure Susceptibility
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Kim DW, Chae SA, Jung KY, Kim JM
- KMID: 2333362
- J Korean Epilepsy Soc.
- 2001 Dec;5(2):119-123.
PURPOSE: Despite decades of clinical experience with the ketogenic diet (KD), its efficacy and mechanisms of action have been examined in few animal studies. The present study was designed to... -
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