- NAD + and Vascular Dysfunction: From Mechanisms to Therapeutic Opportunities
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Abdellatif M, Bugger H, Kroemer G, Sedej S
- KMID: 2531861
- J Lipid Atheroscler.
- 2022 May;11(2):111-132.
- doi: 10.12997/jla.2022.11.2.111
Nicotinamide adenine dinucleotide (NAD + ) is an essential and pleiotropic coenzyme involved not only in cellular energy metabolism, but also in cell signaling, epigenetic regulation, and post-translational protein modifications.... -
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- Effects of Short Term Adiponectin Receptor Agonism on Cardiac Function and Energetics in Diabetic db/db Mice
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Tarkhnishvili A, Koentges C, Pfeil K, Gollmer J, Byrne NJ, Vosko I, Lueg J, Vogelbacher L, Birkle S, Tang S, Mwinyella TBN, Hoffmann MM, Odening KE, Michel NA, Wolf D, Stachon P, Hilgendorf I, Wallner M, Ljubojevic-Holzer S, Lewinski Dv, Rainer P, Sedej S, Sourij H, Bode C, Zirlik A, Bugger H
- KMID: 2531858
- J Lipid Atheroscler.
- 2022 May;11(2):161-177.
- doi: 10.12997/jla.2022.11.2.161
Objective: Impaired cardiac efficiency is a hallmark of diabetic cardiomyopathy in models of type 2 diabetes. Adiponectin receptor 1 (AdipoR1) deficiency impairs cardiac efficiency in non-diabetic mice, suggesting that hypoadiponectinemia... -
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