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Host-Microbiome Interactions in Alcoholic Liver Disease

Chen P, Schnabl B

  • KMID: 1774555
  • Gut Liver.
  • 2014 May;8(3):237-241.
Alcoholic liver disease is a leading cause of morbidity and liver-related death worldwide. Intestinal bacterial overgrowth and dysbiosis induced by ethanol ingestion play an important role in the pathogenesis of...
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From intestinal dysbiosis to alcohol-associated liver disease

Mendes BG, Schnabl B

Alcohol-associated intestinal dysbiosis and bacterial overgrowth can lead to a dysregulation of tryptophan metabolism and lower production of indoles. Several of these indole derivatives are aryl hydrocarbon receptor ligands that,...
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