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Blood–brain barrier disruption caused by neonatal sevoflurane-induced depends on exposure time and is reversible in mice

Sun Z, Satomoto M, Adachi YU, Makita K

No abstract available.
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Pregabalin-induced hypoglycemia in a dialysis patient

Tamura T, Adachi YU, Satomoto M

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Pregabalin-induced hypoglycemia in a dialysis patient

Masaki H, Tamura T, Adachi YU, Satomoto M

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Apocynin preserves glutamatergic neurons in the basolateral amygdala in mice with neonatal sevoflurane exposure

Sun Z, Satomoto M, Adachi YU, Makita K

BACKGROUND: Neonatal exposure to anesthetics induces neuronal apoptosis and long-term cognitive dysfunction in rodents. We showed that the nicotinamide adenine dinucleotide phosphate-oxidase inhibitor apocynin not only reduces neurotoxicity by decreasing...
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A low dose of droperidol decreases the desflurane concentration needed during breast cancer surgery: a randomized double-blinded study

Satomoto M, Adachi YU, Makita K

BACKGROUND: Droperidol (DHB) reportedly reduces the dose of propofol needed to achieve hypnosis when anesthesia is induced and decreases the bispectral index (BIS) in propofol-sedated patients during spinal anesthesia. We...
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Therapeutic effects of intravenous administration of bone marrow stromal cells on sevoflurane-induced neuronal apoptosis and neuroinflammation in neonatal rats

Sun Z, Satomoto M, Makita K

BACKGROUND: Sevoflurane exposure during the early postnatal period causes neuroinflammation and neuronal apoptosis in rodents. Bone marrow stromal cells (BMSCs) have been shown to protect and repair the damaged central...
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The determinants of propofol induction time in anesthesia

Adachi YU, Satomoto M, Higuchi H, Watanabe K

BACKGROUND: The required dose of anesthetics is generally smaller in patients with low cardiac output (CO). A high CO decreases the blood concentration of anesthetics during induction and maintenance of...
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