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Smad3 deficiency accelerates tongue wound healing via epithelial  cell-extracellular matrix interactions

Taguchi C, Sato F, Wang C, Nakamura S, Oikawa K, Bhawal UK, Okada H, Arikawa K

Aberrant wound closure occurs in a broad range of wounds and scars, and the altered regulation of transcription factors in wound areas can account for both of those conditions. This...
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PD-L1 expression correlated with p53 expression in oral squamous cell carcinoma

Tojyo I, Shintani Y, Nakanishi , Okamoto K, Hiraishi Y, Fujita S, Enaka M, Sato F, Muragaki Y

BACKGROUND: Programmed cell death ligand 1 (PD-L1) is an immune checkpoint molecule that attenuates the immune response. PD-L1 contributes to failed antitumor immunity; thereby, blockade of PD-L1 with monoclonal antibody...
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