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Steroidal Saponins from Dracaena humilis (Dracaenaceae) and their Chemotaxonomic Significance

Mouzié CM, Ponou BK, Fouedjou RT, Teponno RB, Tapondjou LA

A new steroidal saponin, (23S,24S)-spirosta-5,25(27)-diene-1β,3β,23,24-tetrol 1-O-((2,3-diacetyl-α-Lrhamnopyranosyl)-(1→2)-[β-D-xylopyranosyl-(1→3)]-α-L-arabinopyranoside)-24-O-β-D-glucopyranoside (humilisoside) together with the known β-sitosterol 3-O-glucopyranoside, adenosine, dioscin, and methylprotodioscin were isolated from the leaves of Dracaena humilis. Their structures were elucidated by...
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Preparation and efficacy of freeze-dried inactivated vaccine against bovine viral diarrhea virus genotypes 1 and 2, bovine herpes virus type 1.1, bovine parainfluenza-3 virus, and bovine respiratory syncytial virus

El Fadeel MRA, El-Dakhly AT, Allam AM, Farag TK, El-kholy AAM

Purpose: Bovine respiratory disease is a worldwide health concern in the feedlot cattle causing morbidity and mortality in young with major economic losses to the producer. Programs of vaccination are...
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Ficus exasperata Vahl leaves extract attenuates motor deficit in vanadium-induced parkinsonism mice

Adekeye AO, Irawo GJ, Fafure AA

Medicinal herbs have played significant roles in the treatment of various diseases in humans and animals. Sodium metavanadate is a potentially toxic environmental pollutant that induces oxidative damage, neurological disorder,...
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Pharmacological Activities and Applications of Spicatoside A

Ramalingam M, Kim SJ

Liriopogons (Liriope and Opiopogon) species are used as a main medicinal ingredient in several Asian countries. The Liriopes Radix (tuber, root of Liriope platyphylla) has to be a promising candidate...
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QS-21 enhances the early antibody response to oil adjuvant foot-and-mouth disease vaccine in cattle

Çokçalışkan C, Türkoğlu T, Sareyyüpoğlu B, Uzunlu E, Babak A, Özbilge B, Gülyaz V

PURPOSE: One of the most important tools against foot-and-mouth disease, a highly contagious and variable viral disease of cloven-hoofed animals, is vaccination. However, the effectiveness of foot-and-mouth disease vaccines on...
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Chemical Constituents from Leaves of Acanthopanax henryi (II)

Li Z, Li XJ, Kwon OK, Wang X, Zou QP, Liu XQ, Lee HK

Nineteen compounds, including one organic acid (1), one anthraquinone (2), one amide (3), and sixteen triterpenoid saponins (4 - 19) were isolated from the leaves of Acanthopanax henryi (Oliv.) Harms...
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Enhancement of Exercise Capacity by Black Ginseng Extract in Rats

Jo GS, Chai HY, Ji HJ, Kang MH, Kang SJ, Ji JG, Kim DJ, Lee BJ

  • KMID: 2312078
  • Lab Anim Res.
  • 2010 Sep;26(3):279-286.
This study was carried out to investigate an enhancing effect of black ginseng extract (BGE) on exercise capacity in an endurance exercising animal model. Fifty Sprague-Dawley rats were assigned to...
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Neuroprotective Effect of Ginseng Total Saponins in Experimental Traumatic Brain Injury

Ji YC, Kim YB, Park SW, Hwang SN, Min BK, Hong HJ, Kwon JT, Suk JS

In the present study, we investigated whether ginseng total saponins (GTSs) protect hippocampal neurons after experimental traumatic brain injury (TBI) in rats. A moderate-grade TBI was made with the aid...
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Effect of Korean Red Ginseng Saponin on Cochlear Damage Induced by Noise Exposure

Sin GC, Lee SH, Nam BH, Park CI, Nam KY

  • KMID: 2274739
  • Korean J Otolaryngol-Head Neck Surg.
  • 2000 Aug;43(8):804-807.
BACKGROUND AND OBJECTIVES: Exposure to noise results in pertubations of cochlear microcirculation. There is evidence that these events are mediated, in part, by the calcium channel. The subsequent decrease in...
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Inhibitory effects of ginseng saponins on c-fos mRNA expression and the proliferation of rat aortic vascular smooth muscle cells stimulated by angiotensin II

Choi W, Jung JY, Kim HS, Yun YP, Park JD, Ahn HY

  • KMID: 1562322
  • Korean J Physiol Pharmacol.
  • 1998 Apr;2(2):201-207.
To evaluate the possibility that the ginseng saponins could be developed as an anti-arteriosclerotic agent, we examined the inhibitory effects of ginseng saponins (total saponin(TS), panaxatriol(PT), panaxadiol(PD)) on the expression of c-fos mRNA...
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Study on ginseng protopanaxadiol and protopanaxatriol saponins-induced antinociception

Shin YH, Kim SC, Han JW, Kim DH, Han SS, Shin DH, Nah SY

  • KMID: 1554550
  • Korean J Physiol Pharmacol.
  • 1997 Apr;1(2):143-149.
We studied the effects of ginseng protopanaxadiol (PD) and protopanaxatriol (PT) saponins on the analgesia using several pain tests such as writhing, formalin, and tail-flick test. Using mouse, pretreatment of PD or PT...
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