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The present study was carried out to examine the mechanisms of the synergistic interaction of PAF and A23187 mediated platelet aggregation. We found that platelet aggregation mediated by subthreshold concentrations...
Shah BH, Siddiqui A, Qureshi KA, Khan M, Rafi S, Ujan VA, Yakoob MY, Rasheed H, Saeed SA
KMID: 755026
Exp Mol Med.
1999 Mar;31(1):42-46.
Our previous studies have shown that subthreshold concentrations of two platelet
agonists exert synergistic effects on platelet aggregation. Here we studied the
mechanism of synergistic interaction of 5-hydroxytryptamine (5-HT) and
epinephrine mediated platelet...
Shah BH, Rasheed H, Rahman IH, Shariff AH, Khan FL, Rahman HB, Hanif S, Saeed SA
KMID: 1457534
Exp Mol Med.
2001 Dec;33(4):226-233.
Our recent studies have shown that co-activation of Gq and Gi proteins by 5-hydroxytryptamine (5-HT) and adrenaline show synergism in human platelet aggregation. This study was conducted to examine the...