- Multiple epidural fibrin glue patches in a patient with spontaneous intracranial hypotension:A case report
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Lee YG, Sa M, Oh IS, Lim JA, Woo NS, Kim JH
- KMID: 2454820
- Anesth Pain Med.
- 2019 Jul;14(3):335-340.
- doi: 10.17085/apm.2019.14.3.335
BACKGROUND: Spontaneous intracranial hypotension (SIH) is a condition caused by spontaneous leakage of cerebrospinal fluid, with postural headache as the primary symptom. Orthostatic headache caused by SIH is often not... -
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- Generation of Astrocyte-Specific MAOB Conditional Knockout Mouse with Minimal Tonic GABA Inhibition
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Lee JM, Sa M, An H, Kim JMJ, Kwon J, Yoon BE, Lee CJ
- KMID: 2531119
- Exp Neurobiol.
- 2022 Jun;31(3):158-172.
- doi: 10.5607/en22016
Monoamine oxidase B (MAOB) is a key enzyme for GABA production in astrocytes in several brain regions. To date, the role of astrocytic MAOB has been studied in MAOB null... -
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- Analysis of env Subtypes of Porcine Endogenous Retrovirus in SNU Miniature Pigs
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Sa M, Park CG, Hwang ES
- KMID: 2135360
- J Bacteriol Virol.
- 2014 Mar;44(1):75-83.
- doi: 10.4167/jbv.2014.44.1.75
All xenografts from pigs impose infection risk by porcine endogenous retrovirus (PERV). The purpose of this study was to investigate the env constructs with the comparison of the ratio of... -
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- Two-Round Mixed Lymphocyte Reaction for Evaluation of the Functional Activities of Anti-PD-1 and Immunomodulators
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Kwon M, Choi YJ, Sa M, Park SH, Shin EC
- KMID: 2429837
- Immune Netw.
- 2018 Dec;18(6):e45.
- doi: 10.4110/in.2018.18.e45
Immune checkpoint inhibitors (ICIs), such as anti-PD-1 and anti-PD-L1 Abs, have shown efficacy for the treatment of various cancers. Although research has actively sought to develop new ICIs and immunomodulators,... -
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- Orai1 and Orai3 in Combination with Stim1 Mediate the Majority of Store-operated Calcium Entry in Astrocytes
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Kwon J, An H, Sa M, Won J, Shin JI, Lee CJ
- KMID: 2368654
- Exp Neurobiol.
- 2017 Feb;26(1):42-54.
- doi: 10.5607/en.2017.26.1.42
Astrocytes are non-excitable cells in the brain and their activity largely depends on the intracellular calcium (Ca²âº) level. Therefore, maintaining the intracellular Ca²⺠homeostasis is critical for proper functioning of... -
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- Unaltered Tonic Inhibition in the Arcuate Nucleus of Diet-induced Obese Mice
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Sa M, Lee JM, Park MG, Lim J, Joseph Kim JM, Koh W, Yoon BE, Lee CJ
- KMID: 2531118
- Exp Neurobiol.
- 2022 Jun;31(3):147-157.
- doi: 10.5607/en22014
The principal inhibitory transmitter, γ-aminobutyric acid (GABA), is critical for maintaining hypothalamic homeostasis and released from neurons phasically, as well as from astrocytes tonically. Although astrocytes in the arcuate nucleus... -
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- Fatty Acid Increases cAMP-dependent Lactate and MAO-B-dependent GABA Production in Mouse Astrocytes by Activating a G(αs) Protein-coupled Receptor
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Lee N, Sa M, Hong YR, Lee CJ, Koo J
- KMID: 2424731
- Exp Neurobiol.
- 2018 Oct;27(5):365-376.
- doi: 10.5607/en.2018.27.5.365
Medium-chain fatty acids (MCFAs) are mostly generated from dietary triglycerides and can penetrate the blood-brain barrier. Astrocytes in the brain use MCFAs as an alternative energy source. In addition, MCFAs... -
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