- STP-A11, an oncoprotein of Herpesvirus saimiri augments both NF-kappaB and AP-1 transcription activity through TRAF6
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Jeong S, Cho IR, An WG, Jhun BH, Lee BS, Park K, Chung YH
- KMID: 1103681
- Exp Mol Med.
- 2007 Feb;39(1):56-64.
Herpesvirus saimiri (HVS), a member of the gamma-herpesvirus family, encodes an oncoprotein called Saimiri Transforming Protein (STP) which is required for lymphoma induction in non-human primates. However, a detailed mechanism... -
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- Triptolide downregulates Rac1 and the JAK/STAT3 pathway and inhibits colitis-related colon cancer progression
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Wang Z, Jin H, Xu R, Mei Q, Fan D
- KMID: 1009393
- Exp Mol Med.
- 2009 Oct;41(10):717-727.
- doi: 10.3858/emm.2009.41.10.078
Triptolide, a diterpenoid triepoxide from the traditional Chinese medicinal herb Tripterygium wilfordii Hook. f., is a potential treatment for autoimmune diseases as well a possible anti-tumor agent. It inhibits proliferation... -
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