- Anti-inflammatory activity of compounds isolated from Astragalus sinicus L. in cytokine-induced keratinocytes and skin
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Kim BH, Oh I, Kim JH, Jeon JE, Jeon B, Shin J, Kim TY
- KMID: 2155352
- Exp Mol Med.
- 2014 Mar;46(3):e87.
- doi: 10.1038/emm.2013.157
Inflammation is a part of the complex biological responses of a tissue to injury that protect the organ by removing injurious stimuli and initiating the healing process, and is considered... -
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- Benzoxathiol derivative BOT-4-one suppresses L540 lymphoma cell survival and proliferation via inhibition of JAK3/STAT3 signaling
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Kim BH, Min YS, Choi JS, Baeg GH, Kim Y, Shin JW, Kim TY, Ye SK
- KMID: 1009971
- Exp Mol Med.
- 2011 May;43(5):313-321.
- doi: 10.3858/emm.2011.43.5.035
Persistently activated JAK/STAT3 signaling pathway plays a pivotal role in various human cancers including major carcinomas and hematologic tumors, and is implicated in cancer cell survival and proliferation. Therefore, inhibition... -
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