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TRPC3 cation channel plays an important role in proliferation and differentiation of skeletal muscle myoblasts

Woo JS, Cho CH, Kim DH, Lee EH

During membrane depolarization associated with skeletal excitation-contraction (EC) coupling, dihydropyridine receptor [DHPR, a L-type Ca2+ channel in the transverse (t)-tubule membrane] undergoes conformational changes that are transmitted to ryanodine receptor...
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Calcium Uptake and Release through Sarcoplasmic Reticulum in the Inferior Oblique Muscles of Patients with Inferior Oblique Overaction

Kim HS, Chang YH, Kim DH, Park SR, Han SH, Lee JB

We characterized and compared the characteristics of Ca2+ movements through the sarcoplasmic reticulum of inferior oblique muscles in the various conditions including primary inferior oblique overaction (IOOA), secondary IOOA, and...
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Doxorubicin-induced reactive oxygen species generation and intracellular Ca2+increase are reciprocally modulated in rat cardiomyocytes

Kim SY, Kim SJ, Kim BJ, Rah SY, Chung SM, Im MJ, Kim UH

  • KMID: 1098088
  • Exp Mol Med.
  • 2006 Oct;38(5):535-545.
Doxorubicin (DOX) is one of the most potent anticancer drugs and induces acute cardiac arrhythmias and chronic cumulative cardiomyopathy. Though DOX-induced cardiotoxicity is known to be caused mainly by ROS...
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