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Pertussis Accompanying Recent Mycoplasma Infection in a 10-Year-Old Girl

Cheon MK, Na H, Han SB, Kwon HJ, Chun YH, Kang JH

Recently, the incidence of pertussis has been increasing; however, reports on mixed infection of pertussis with other respiratory pathogens are rare in highly immunized populations. We report the case of...
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Bronchiolitis Obliterans Associated with Stevens-Johnson Syndrome: A Case Report

Park H, Ko YB, Kwon HS, Lim CM

We report a case of bronchiolitis obliterans associated with Stevens-Johnson syndrome. A 59-year-old man presented with respiratory distress that gradually worsened over 3 months. He had been diagnosed with Stevens-Johnson...
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Emergence of macrolide resistance and clinical use of macrolide antimicrobials in children

Choi EH

Macrolide antimicrobial agents including erythromycin, roxithromycin, clarithromycin, and azithromycin are commonly used in the treatment of respiratory tract infections in children. Newer macrolides that have structural modifications of older drug...
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Roxithromycin Suppresses MUC5B/8 Mucin Genes and Mucin Production in Airway Epithelial Cells

Woo HJ, Min MK, Bae CH, Song SY, Kim YD

  • KMID: 2141201
  • Korean J Otorhinolaryngol-Head Neck Surg.
  • 2008 Jul;51(7):617-622.
BACKGROUND AND OBJECTIVES: Macrolide antibiotics are known to inhibit mucus hypersecretion in patients with chronic airway diseases, but its action mechanism is unclear. Several reports demonstrated that macrolides significantly inhibited...
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Co-prescribing Patterns of Contraindicated Drugs for the Elderly Patients in Busan

Choi NK, Jung SY, Park BJ

  • KMID: 2233459
  • Korean J Epidemiol.
  • 2008 Jun;30(1):128-136.
PURPOSE: To estimate the prevalence of co-prescribing contraindicated drugs for elderly patients in Busan. METHODS: We used the Health Insurance Review Agency (HIRA) claims database. Study population consisted of elderly patients...
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Effect of Macrolide on the MUC4 Gene Expression in Human Airway Epithelial Cells

Woo HJ, Lee SC, Choi YS, Choi SW, Kim MH, Jeon BS, Song SY, Kim YD, Bai CH

  • KMID: 1875406
  • Korean J Otorhinolaryngol-Head Neck Surg.
  • 2007 Sep;50(9):784-788.
BACKGROUND AND OBJECTIVES: Mucin gene expression and mucin secretion are highly increased by inflammatory airway diseases such as asthma, chronic bronchitis and rhinosinusitis. Macrolide antibiotics is considered one of the...
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A Case of Tinea Barbae Caused by Trichophyton mentagrophytes

Lim JW, Kim SH, Suh MK, Park SK, Lee YH, Ha GY, Kim JR

  • KMID: 2116321
  • Korean J Dermatol.
  • 2007 Mar;45(3):262-265.
We report a case of tinea barbae in a 51-year-old man, who presented with erythematous pustules on the upper lip, and a relatively well-defined pustular patch on his left cheek....
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A Case of Cutaneous alternariosis due to Alternaria alternata

Lee JC, Kim HY, Lee WJ, Lee SJ, Kim DW, Jun JB, Suh SB

  • KMID: 1513581
  • Korean J Med Mycol.
  • 2007 Mar;12(1):27-30.
Alternaria is a common saprophyte that is not usually pathogenic in humans. However, infections by the fungus have occasionally been documented, occurring mostly in immunocompromised patients. We report a case...
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Retraction: Roxithromycin Treatment of Tsutsugamushi Disease (Scrub Typhus) in Children

Park HJ, Lee KY

  • KMID: 2279078
  • Korean J Pediatr.
  • 2005 Oct;48(10):1149-1149.
No abstract available.
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A Case of Acute Respiratory Distress Syndrome by Nosocomial Mycoplasma Pneumonia Associated with Cold Agglutinin Disease in Primary CNS Lymphoma

Im E, Kim JS, Hahn JS, Yang WI

  • KMID: 2285093
  • Infect Chemother.
  • 2005 Aug;37(4):237-241.
Although Mycoplasma pneumonia is frequently observed in immunocompromized patient if, rarely results in acute respiratory distress syndrome (ARDS). The cold agglutinin is positive in 33-76% of patients with M. pneumonia...
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A Case of Group A Streptococcal Pneumonia with Empyema and Pericardial Effusion

Chun YH, Lee SY, Choi SL, Jeong DC, Chung SY, Kang JH

Group A streptococcus, also known as Streptococcus pyogenes, is a common bacterial pathogens of the upper respiratory tract and skin infections in children, but this organism is a less common...
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Effect of Roxithromycin and Intranasal Fluticasone Spray in Reducing Symptoms of Chronic Sinusitis, Polyp Size and IL-4 in Allergic Patients

Kim BG, Lee DM, Jo JH, Jung DG, Kang JM, Kim SW

  • KMID: 2223307
  • J Rhinol.
  • 2003 Nov;10(1, 2):37-41.
Nasal polyp is an intractable condition usually associated with chronic hyperplastic sinusitis with allergic rhinitis. IL-4 is known to contribute to the inflammatory reaction by enhancing binding of inflammatory cells...
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Roxithromycin Treatment of Tsutsugamushi Disease (Scrub Typhus) in Children

Park HJ, Lee KY

  • KMID: 2335747
  • J Korean Pediatr Soc.
  • 2003 Jul;46(7):710-713.
PURPOSE: Although chloramphenicol and doxycycline have been used for the treatment of tsutsugamuchi disease, a difficulty exists in determining which drugs to use in treating children because of potential complications...
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Determination of Roxithromycin by Liquid Chromatography/Mass Spectrometry after Multiple-Dose Oral Administration in Broilers

Lim JH, Park BK, Yun HI

  • KMID: 1099819
  • J Vet Sci.
  • 2003 Apr;4(1):35-39.
A highly sensitive and specific method for the determination of roxithromycin in broiler tissues by LC/MS was developed and validated. A dichloromethane extract of the sample was separated on C18...
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Effect of Macrolides on the Interleukin-1beta-mediated MUC2/5AC Genes Expression and Mucin Secretion in Human Airway Epithelial Cells

Kim YD, Cho JS, Kim HS, Song SY

  • KMID: 2131801
  • J Rhinol.
  • 2002 Nov;9(1, 2):52-56.
BACKGROUND AND OBJECTIVES: Macrolide is a relatively effective drug in chronic bronchiolitis and chronic sinusitis with mucous hypersecretion. However, the anti-secretory effect of macrolide is not clear. The aim of...
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Simultaneous Determination of Various Macrolides by Liquid Chromatography/Mass Spectrometry

Hwang YH, Lim JH, Park BK, Yun HI

  • KMID: 1095368
  • J Vet Sci.
  • 2002 Jun;3(2):103-108.
Macrolides are frequently used in veterinary medicine as therapeutic and preventive agents for various diseases. It is difficult to determine macrolides simultaneously with conventional methods due to their similar structures....
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Selective Bowel Decontamination for the Prevention of Infection in Acute Myelogenous Leukemia: A Prospective Randomized Trial

Lee DG, Choi SM, Choi JH, Yoo JH, Park YH, Kim YJ, Lee S, Min CK, Kim HJ, Kim DW, Lee JW, Min WS, Shin WS, Kim CC

  • KMID: 1758676
  • Korean J Intern Med.
  • 2002 Mar;17(1):38-44.
BACKGROUND: Infection is still a frequent cause of morbidity and mortality in acute myelogenous leukemia (AML) patients receiving chemotherapy. Recently the main cause of infection has changed from gram-negative to...
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Selective bowel decontamination for the prevention of infection in acute myelogenous leukemia: A prospective randomized trial

Lee DG, Yoon JM, Cho JH, Choi SM, Park YH, Kim YJ, Lee S, Choi JH, Lee JW, Shin WS, Kim CC

  • KMID: 2253031
  • Korean J Med.
  • 2001 Feb;60(2):167-174.
BACKGROUND: Infections are still a frequent cause of morbidity and mortality in patients with hematologic malignancies. Antimicrobial prophylaxis in neutropenic patients has been practised for several decades. But, recently the...
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A Case of Bacillus Cereus Infection with Pneumonia and Bactermia

Park JH, Jang AS, Han SW, Kim YC, Lee KR, Park SH, Choi SI, Shin MG, Kim SH

Bacillus species are aerobic, gram-positive, spore forming rods that are widely distributed in soil, dust, stream, and other environmental sources and are regarded as natural organism. But certain species of...
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A Case of Pityriasis Lichenoides et Varioliformis Acuta in children: Treatment with roxithromycin

Park JM, Bahn JY, Kwon SJ, Yu HJ

  • KMID: 2230374
  • Korean J Dermatol.
  • 2000 Sep;38(9):1267-1269.
Pityriasis lichenoides et varioliformis acuta is a cutaneous disease of unknown origin characterized by an acute polymorphous eruption which heals with superficial scarring and pigmentation. It occurs mainly in young...
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