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Potential Candidates for Biomarkers in Bipolar Disorder:A Proteomic Approach through Systems Biology

Ziani PR, Feiten JG, Goularte JF, Colombo R, Antqueviezc B, Géa LP, Rosa AR

Bipolar disorder (BD) is one of the most disabling diseases characterized by severe humor fluctuation. It is accompanied by cognitive and functional impairment in addiction to high suicide rates. BD...
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Validation of the Korean Version of the Biological Rhythms Interview of Assessment in Neuropsychiatry

Cho CH, Jung SY, Kapczinski F, Rosa AR, Lee HJ

OBJECTIVE: The Biological Rhythms Interview of Assessment in Neuropsychiatry (BRIAN) is a scale used to clinically evaluate disturbances in biological rhythm. In this study, we aimed to examine the reliability...
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Depression and Mania Induce Pro-inflammatory Activation of Macrophages Following Application of Serum from Individuals with Bipolar Disorder

Ferrari P, Parisi MM, Colombo R, Becker M, Fries G, Ascoli BM, Géa LP, Kauer-Sant’anna M, Kapczinski F, Klamt F, Guma FT, Rosa AR, Barbé-Tuana FM

OBJECTIVE: Evidence has suggested that immune imbalance is involved with bipolar disorder (BD); however, its precise mechanism is poorly understood. This study investigated whether biochemical changes in the serum from...
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