- Inhibition of COX-2 Impairs Colon Cancer Liver Metastasis through Reduced Stromal Cell Reaction
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Herrero A, Benedicto A, Romayor I, Olaso E, Arteta B
- KMID: 2515283
- Biomol Ther.
- 2021 May;29(3):342-351.
- doi: 10.4062/biomolther.2020.160
Liver colonization is initiated through the interplay between tumor cells and adhesion molecules present in liver sinusoidal endothelial cells (LSECs). This crosstalk stimulates tumor COX-2 upregulation and PGE 2 secretion.... -
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