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Ritanserin, a 5HT2/1C receptor antagonist, does not block cocaine-induced behavioral alterations and zif268 mRNA expression in the striatum of the rats

Choe ES, Kim JY

  • KMID: 1580932
  • Korean J Physiol Pharmacol.
  • 2000 Oct;4(5):355-359.
Cocaine induces immediate early gene expression and behavioral changes by blocking dopamine transporters in the terminals of nigrostriatal neurons in the striatum. The pharmacological role of serotonin 2/1C (5HT2/1C) receptors in cocaine-induced expression...
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Effects of Concomitant Treatment with Drugs Affecting Monoaminergic Systems on the Clozapine-induced Myoclonic Jerks in Partially Restrained Rats

Lee SK, Kim H, Kim YH, KIm SH, Park CG, Yoon SH

  • KMID: 2334594
  • J Korean Soc Biol Psychiatry.
  • 1999 Jul;6(1):74-80.
This study was performed to investigate the mechanism of the clozapine-induced seizures in partially restrained rats by concomitant treatment with drugs affecting monoaminergic systems. Partially restrained rats treated with acute...
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Effect of Ritanserin on the Circling Movement in the Unilateral Substantia Nigra-Lesioned Rats

Kim IH, Chung YC, Eun HB

  • KMID: 1554198
  • Korean J Psychopharmacol.
  • 1999 Oct;10(2):130-137.
OBJECTIVE: Recently, the serotonin-dopamine interaction is being regarded as a possible mechanism for both less extrapyramidal symptoms and good therapeutic effect on negative symptoms which are outstanding advantages of atypical...
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Antinociceptive Effects of Tramadol on the Neuropathic Pain in Rats

Song KW, Kim HJ, Yum KW

  • KMID: 2335946
  • J Korean Pain Soc.
  • 2001 Dec;14(2):150-155.
BACKGROUND: Tramadol is known to be a weak opioid. However, it has also been shown that tramadol is an effective norepinephrine and serotonin uptake blocker, which may be effective in...
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Amperozide decreases cocaine-induced increase in behavior and immediate early gene expression in the dorsal striatum

Choe ES, Kim JY

  • KMID: 1580933
  • Korean J Physiol Pharmacol.
  • 2000 Oct;4(5):361-367.
Cocaine functions as indirect dopamine and serotonin (5-hydroxytryptamine, 5HT) agonists and induces genomic and behavioral alterations in the striatum. Previously we demonstrated that ritanserin, a 5HT2/1C receptor antagonist, is not responsible for cocaine-induced behavioral...
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The Role of 5-HT Receptors on the Acetylcholine Release from the Rat Striatum

Joo YH, Jung KY, Choi BK

  • KMID: 1607282
  • Korean J Psychopharmacol.
  • 2001 Jun;12(2):140-146.
The aim of this study was to investigate the role of the 5-HT receptors in acetylcholine (ACh) release from the striatum. Slices from the rat striatum and synaptosomes were incubated...
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Effect of Trazodone on the Rat Cerebral Hemodynamics

Hong JY, Byoun WT, Shin HK, Ko SY, Lee WS

  • KMID: 2287015
  • Korean J Psychopharmacol.
  • 1999 Apr;10(1):71-79.
OBJECTIVES: The present study assessed the effect of trazodone on the cerebral hemodynamics of male Sprague-Dawley rats. METHOD: The changes of regional cerebral blood flow(rCBF) and pill arterial diameter were...
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