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Role of Mixed Reflux and Hypomotility with Delayed Reflux Clearance in Patients with Non-cardiac Chest Pain

Ribolsi M, Balestrieri P, Biasutto D, Emerenziani S, Cicala M

  • KMID: 2433452
  • J Neurogastroenterol Motil.
  • 2016 Oct;22(4):606-612.
  • doi: 10.5056/jnm15182
BACKGROUND/AIMS: Gastroesophageal reflux disease (GERD) is the most common cause of non-cardiac chest pain (NCCP). Currently available data reveal a weak relationship between NCCP and dysmotility. Moreover, it is unclear...
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High-resolution Manometry Findings During Solid Swallows Correlate With Delayed Reflux Clearance and Acid Exposure Time in Non-erosive Reflux Disease Patients

Ribolsi M, Biasutto D, Giordano A, Balestrieri P, Cicala M

  • KMID: 2433499
  • J Neurogastroenterol Motil.
  • 2019 Jan;25(1):68-74.
  • doi: 10.5056/jnm18054
BACKGROUND/AIMS: The role of esophageal motility in determining gastroesophageal reflux disease (GERD) severity has not been completely evaluated. A few studies have investigated high-resolution manometry (HRM) patterns during solid swallows....
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Patients With Definite and Inconclusive Evidence of Reflux According to Lyon Consensus Display Similar Motility and Esophagogastric Junction Characteristics

Ribolsi M, Savarino E, Rogers B, Rengarajan A, Coletta MD, Ghisa M, Cicala M, Gyawali CP

  • KMID: 2521157
  • J Neurogastroenterol Motil.
  • 2021 Oct;27(4):565-573.
  • doi: 10.5056/jnm20158
Background/Aims The role of esophageal high-resolution manometry (HRM) within Lyon consensus phenotypes, especially patients with inconclusive gastroesophageal reflux disease (GERD) evidence, has not been fully investigated. In this multicenter, observational study...
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The Lyon Consensus: Does It Differ From the Previous Ones?

Ghisa M, Barberio B, Savarino V, Marabotto E, Ribolsi M, Bodini G, Zingone F, Frazzoni M, Savarino E

  • KMID: 2503999
  • J Neurogastroenterol Motil.
  • 2020 Jul;26(3):311-321.
  • doi: 10.5056/jnm20046
Gastroesophageal reflux disease (GERD) is a complex disorder with heterogeneous symptoms and a multifaceted pathogenetic basis, which prevent a simple diagnostic algorithm or any categorical classification. Clinical history, questionnaires and...
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High-resolution Manometry Determinants of Refractoriness of Reflux Symptoms to Proton Pump Inhibitor Therapy

Ribolsi M, Savarino E, Rogers B, Rengarajan A, Coletta MD, Ghisa M, Cicala M, Gyawali CP

  • KMID: 2507109
  • J Neurogastroenterol Motil.
  • 2020 Oct;26(4):447-454.
  • doi: 10.5056/jnm19153
Background/Aims Impaired esophageal motility and disrupted esophagogastric junction (EGJ) on high-resolution manometry (HRM) have been associated with increased reflux severity in gastroesophageal reflux disease (GERD) patients. However, there are limited data...
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Impaired Colonic Contractility and Intestinal Permeability in Symptomatic Uncomplicated Diverticular Disease

Altomare A, Gori M, Cocca S, Carotti S, Francesconi M, Ribolsi M, Emerenziani S, Perrone G, Morini S, Cicala M, Guarino MPL

  • KMID: 2514687
  • J Neurogastroenterol Motil.
  • 2021 Apr;27(2):292-301.
  • doi: 10.5056/jnm20110
Background/Aims Impaired intestinal motility seems to play a crucial role in symptomatic uncomplicated diverticular disease (SUDD), although the mechanism is not clear. The aim of the present study is to explore...
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