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Antimicrobial Effect of Coptidis rhizome Extract against Mutans Streptococci and Periodontopathogens

Park SN, Lim YK, Kook JK

The purpose of the study was to investigate the antimicrobial activity of the methanol extract of Coptidis rhizome against the type strains of cariogenic bacteria, Streptococcus mutans and Streptococcus sobrinus,...
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A Case of Arisaematis Rhizoma Poisoning

Park S, Yeom S, Han S, Lee S, Ju S

Due to increasing participation in outdoor activities, many people visit the emergency room for various symptoms after mistaking poisonous plants for medicinal herbs. The toxicity of Arisaematis rhizome is due...
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The Effects of an Extract of Atractylodes Japonica Rhizome, SKI3246 on Gastrointestinal Motility in Guinea Pigs

Park JJ, Chon NR, Lee YJ, Park H

  • KMID: 2433474
  • J Neurogastroenterol Motil.
  • 2015 Jul;21(3):352-360.
  • doi: 10.5056/jnm14112
BACKGROUND/AIMS: There are limited therapeutic options available for irritable bowel syndrome with diarrhea (IBS-D). We tested the effects of Atractylodes japonica rhizome, a perennial plant native to North Asia, on...
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Differential Growth Response of A1 and A2 Mating Types of Phytophthora infestans on Rye A and V-8 Juice Agar Media Supplemented with Rhizome Powder of Cyperus rotundus

Singh UP, Sarma BK, Nishimura , Kobayashi , Ogoshi A, Zinkernagel V, Schlenzig , Schober-Butin B, Aust HJ

  • KMID: 2312352
  • Mycobiology.
  • 2001 Sep;29(3):164-169.
A new medium for studies of diversity among populations of A1 and A2 mating types of Phytophthora infestans has been evolved. The rye A agar and V-8 juice agar media...
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Anticolitic Effect of the Rhizome Mixture of Anemarrhena asphodeloides and Coptidis chinensis (AC-mix) in Mice

Jang SE, Jeong JJ, Hyam SR, Han MJ, Kim DH

  • KMID: 2048311
  • Biomol Ther.
  • 2013 Sep;21(5):398-404.
During a screening program to search the anticolitic herbal medicines, 80% ethanol extract of the rhizome of Anemarrhena asphodeloides (AA) was found to potently inhibit the expression of proinflammatory cytokines...
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Immunomodulatory Effects of Dioscoreae Rhizome Against Inflammation through Suppressed Production of Cytokines Via Inhibition of the NF-kappaB Pathway

Kim S, Shin S, Hyun B, Kong H, Han S, Lee A, Lee S, Kim K

Dioscoreae Rhizome (DR) has been used in traditional medicine to treat numerous diseases and is reported to have anti-diabetes and anti-tumor activities. To identify a bioactive traditional medicine with anti-inflammatory...
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Induction of Sexual Stage and Colony Morphology of Some Isolates of Sclerotium rolfsii Causing Spotted Leaf Rot in Plants

Pandey MK, Sarma BK, Singh UP

Twenty-two isolates of Sclerotium rolfsii causing spotted leaf rot from Varanasi, India were grown on 6% Cyperus rotundus rhizome meal agar (CRMA) medium for the induction of athelial stage (Athelia...
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Effect of[6]-Gingerol on Inhibition of Cell Proliferation in MDA-MB-231 Human Breast Cancer Cells

Seo EY, Lee HS, Kim WK

  • KMID: 2257588
  • Korean J Nutr.
  • 2005 Oct;38(8):656-662.
Ginger (Zingiber officinale Roscoe, Zingiberaceae) is one of the most frequently and heavily consumed dietary condiments throughout the world. Besides its extensive use as a spice, the rhizome of ginger...
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DW2007 Ameliorates Colitis and Rheumatoid Arthritis in Mice by Correcting Th17/Treg Imbalance and Inhibiting NF-κB Activation

Lim SM, Lee SY, Jeong JJ, Choi HS, Chang HB, Kim DH

In the previous study, the rhizome mixture of Anemarrhena asphodeloides and Coptis chinensis (DW2007), improved TNBS-, oxazolone-, or DSS-induced colitis in mice by regulating macrophage activation. Therefore, to understand the...
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Identification of Neuroactive Constituents of the Ethyl Acetate Fraction from Cyperi Rhizoma Using Bioactivity-Guided Fractionation

Sim Y, Choi JG, Gu PS, Ryu B, Kim JH, Kang I, Jang DS, Oh MS

Cyperi Rhizoma (CR), the rhizome of Cyperus rotundus L., exhibits neuroprotective effects in in vitro and in vivo models of neuronal diseases. Nevertheless, no study has aimed at finding the...
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Tanshinone IIA Protects Endothelial Cells from Hâ‚‚Oâ‚‚-Induced Injuries via PXR Activation

Zhu H, Chen Z, Ma Z, Tan H, Xiao C, Tang X, Zhang B, Wang Y, Gao Y

Tanshinone IIA (Tan IIA) is a pharmacologically active substance extracted from the rhizome of Salvia miltiorrhiza Bunge (also known as the Chinese herb Danshen), and is widely used to treat...
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Apoptotic Activity of Curcumin and EF-24 in HTB-41 Human Salivary Gland Epidermoid Carcinoma Cells

Kim JW, Lee SA, Go DS, Park BS, Kim SG, Yu SK, Oh JS, Kim CS, Kim J, Park JT, Kim DK

Curcumin (diferuloylmethane), a constituent of turmeric powder derived from the rhizome of Curcuma longa, has been shown to inhibit the growth of various types of cancer cells by regulating cell...
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Antibiotic Components from the Rhizomes of Curcuma zedoaria

Jeong CS, Shim SH

Two terpenoids, including one uniquely aromatized one (1), were isolated from CH2Cl2-soluble fraction of MeOH extracts of Curcuma zedoaria. They were identified to be a sesquiterpene ketolactone (1) and orobanone...
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Coptis chinensis Extract Inhibits the Production of Inflammatory Mediators and Delayed Type Hypersensitivity in Mice

Lee YA, Hong SJ, Lee SH, Kim KS, Park EK, Jung K, Han CS, Yoo MC, Yang HI

BACKGROUND: Coptis chinensis rhizome has been used as a medicinal herb in traditional Oriental medicine. We investigated the effects of Coptis chinensis extract on inflammatory mediators and delayed type hypersensitivity...
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Effects of Adriamycin or CP-2 to the Rectal Mucosae of Mouse Implanted with Ehrlich Carcinoma Cells: An Autoradiographic Study

Wang JW, Ko JS, Ahn ET, Park KH, Park DK

  • KMID: 2224487
  • Korean J Anat.
  • 2005 Dec;38(6):505-514.
This experiment was performed to evaluate the morphological responses of the rectal intestinal glands of the mouse, inoculated with Ehrlich carcinoma cells, following administration of adriamycin or composition of the...
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Baicalein Inhibits the Migration and Invasion of B16F10 Mouse Melanoma Cells through Inactivation of the PI3K/Akt Signaling Pathway

Choi EO, Cho EJ, Jeong JW, Park C, Hong SH, Hwang HJ, Moon SK, Son CG, Kim WJ, Choi YH

Baicalein, a natural flavonoid obtained from the rhizome of Scutellaria baicalensis Georgi, has been reported to have anticancer activities in several human cancer cell lines. However, its antimetastatic effects and...
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The Application of DNA Chip Technology to Identify Herbal Medicines: an Example from the Family Umbelliferae

Kim PH, Park J, Kim YS, Suh Y

Comparative molecular analysis has been frequently adopted for the authentication of herbal medicines as well as the identification of botanical origins. Roots and rhizomes of the family Umbelliferae have been...
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Phytochemical Constituents from the Rhizomes of Osmunda japonica Thunb and Their Anti-oxidant Activity

Woo KW, Jung JK, Lee HJ, Kim TM, Kim MS, Jung HK, An B, Ham SH, Jeon BH, Cho HW

Eleven compounds (1–11) were isolated from the rhizomes of Osmunda japonica, and their structures were elucidated based on 1H, 13C-NMR and LC-IT-TOF MS data. Of these compounds, all compounds (1...
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Effects of Curcumin on Apoptosis in SW480 Human Colon Cancer Cell Line

Choi OS, Kim WK

  • KMID: 2269720
  • Korean J Nutr.
  • 2004 Jan;37(1):31-37.
Curcumin, a natural compound extracted from rhizomes of Curcuma longa, has been shown to possess potent antiinflammatory and anti-tumor activity. The mechanism by which curcumin initiates apoptosis remains poorly understood....
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Atractylochromene Is a Repressor of Wnt/beta-Catenin Signaling in Colon Cancer Cells

Shim AR, Dong GZ, Lee HJ, Ryu JH

Wnt/beta-catenin signaling pathway was mutated in about 90% of the sporadic and hereditary colorectal cancers. The abnormally activated beta-catenin increases the cancer cell proliferation, differentiation and metastasis through increasing the...
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