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An Interaction Model of IL-4 and IFN-gamma Gene SNPs in Relation to Atopy

  • KMID: 2234480
  • Korean J Asthma Allergy Clin Immunol.
  • 2008 Mar;28(1):45-52.
BACKGROUND: Asthma is a common complex genetic disease. While the T-helper cell 1 pathway is determined by cytokine interferon-gamma (IFN-gamma), the T-helper cell 2 pathway is determined by IL-4. These...
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Long-Term Effects of Diesel Exhaust Particles on Airway Inflammation and Remodeling in a Mouse Model

Kim BG, Lee PH, Lee SH, Kim YE, Shin MY, Kang Y, Bae SH, Kim MJ, Rhim T, Park CS, Jang AS

PURPOSE: Diesel exhaust particles (DEPs) can induce and trigger airway hyperresponsiveness (AHR) and inflammation. The aim of this study was to investigate the effect of long-term DEP exposure on AHR,...
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