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Redox signaling: hydrogen peroxide as intracellular messenger

Rhee SG

  • KMID: 1029931
  • Exp Mol Med.
  • 1999 Jun;31(2):53-59.
Although superoxide anions (O2.-) and H2O2 are generally considered to be toxic by-products of respiration, recent evidence suggests that the production of these reactive oxygen species (ROS) might be an integral component...
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Homogeneity of Phospholipase C of Bovine Uterus and Seminal Vesicle Compared with Brain Isozymes

Kim JH, Lee KY, Rhee SG

Phosphoinositide-specific Phospholipase C (PI-PLC) is a second messenger of signal transducer on cell membrane. In the previous study, PLC of bovine brain has been purified three isozymes. In this paper,...
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Increased Expression of Phospholipase C-gamma1 Activator Protein, AHNAK in Human Lung Cancer Tissues

Oh YJ, Park CS, Choi SY, Cheong SC, Lee SM, Hwang SC, Lee YH, Hahn MH, Lee KB, Ryu HY, Bae YS, Rhee SG

  • KMID: 2318215
  • Tuberc Respir Dis.
  • 1999 Sep;47(3):347-355.
BACKGROUND: Phospholipase C(PLC) plays a central role in cellular signal transduction and is important in cellular growth, differentiation and transformation. There are currently ten known mammalian isozymes of PLC reported...
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Distribution of Thioredoxin Peroxidases and Expression of Thioredoxin Peroxidases in Various Human Cancers

Kim HJ, Hwang SC, Noh DY, Kim SK, Lee WY, Chae HZ, Rhee SG

  • KMID: 2306383
  • Korean J Med.
  • 1997 Feb;52(2):165-173.
OBJECTIVES: Thioredoxin peroxidase(TPx), which does not exhibit similar activity and amino acid sequence homology to conventional antioxidant enzymes has been purified from S cerevisiae and bovine brain. Natural killer enhancing...
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