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Antiplatelet Effect of Cudraxanthone L Isolated from Cudrania tricuspidata via Inhibition of Phosphoproteins

Shin JH, Rhee MH, Kwon HW

Cudrania tricuspidata (C. tricuspidata) is a deciduous tree found in Japan, China and Korea. The root, stems, bark and fruit of C. tricuspidata has been used as traditional herbal remedies...
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An Investigation Study on the Role and Performance Ability of Physical Therapists in the Community Care System for Elderly

Lee SY, Choi SH, Ha KJ, Rhee MH

Purpose: A survey was conducted to investigate the role, priority, and awareness of physical therapists in the community care system for the elderly. Methods: Nine hundred ninety-three physical therapists were invited...
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Molecular Detection and Subtyping of Blastocystis in Korean Pigs

Paik S, Jung BY, Lee H, Hwang MH, Han JE, Rhee MH, Kim TH, Kwon OD, Kwak D

Blastocystis is one of the most commonly detected genera of protozoan parasites in the human intestines as well as the intestines of many other species such as pigs in several...
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Serological Detection of Antibodies against Anaplasma spp. in Cattle Reared in the Gyeongsangbuk-do, Korea

Seo MG, Ouh IO, Lee SH, Son UH, Geraldino , Rhee MH, Kwon OD, Kim TH, Kwak D

Anaplasmosis is a tick-borne, non-contagious, zoonotic disease caused by Anaplasma spp., which include Anaplasma marginale, A. centrale, A. phagocytophilum, A. platys, A. ovis, and A. bovis. Recently, in Korea, the...
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Artemisia capillaris Thunb. inhibits melanin synthesis activity via ERK-dependent MITF pathway in B16/F10 melanoma cells

Saba E, Oh MJ, Lee YY, Kwak D, Kim S, Rhee MH

Genus Artemisia occurs as a hardy plant and has a wide range of culinary and medicinal features. In this study, we aimed to describe the melanin inhibitory activity of one...
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Erratum: Blood flow-improving activity of methyl jasmonate-treated adventitious roots of mountain ginseng

Ban YH, Cha Y, Choi J, An ES, Lee JY, Han NR, Seo DW, Jung G, Jeong DH, Rhee MH, Choi EK, Kim YB

In this article, So-Young Park is inadvertently omitted from the listed author names. In the Acknowledgement section, funding source is incorrectly cited and has been changed upon request of authors.
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Blood flow-improving activity of methyl jasmonate-treated adventitious roots of mountain ginseng

Ban YH, Cha Y, Choi J, An ES, Lee JY, Han NR, Seo DW, Jung G, Jeong DH, Rhee MH, Choi EK, Kim YB

Ginsenosides from Panax ginseng are well known for their diverse pharmacological effects including antithrombotic activity. Since adventitious roots of mountain ginseng (ARMG) also contain various ginsenosides, blood flow-improving effects of...
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Solanum lycopersicum (tomato) ethanol extract elicits anti-inflammatory effects via the nuclear factor kappa B pathway and rescues mice from septic shock

Saba E, Oh MJ, Kwak D, Roh SS, Kwon HW, Kim SD, Rhee MH

Solanum lycopersicum, commonly known as tomato, is widely used in raw, cooked, or liquid forms because it contains nutritional compounds that are beneficial for human health, including carotenoids, lycopene, ascorbic...
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Diversity of vir Genes in Plasmodium vivax from Endemic Regions in the Republic of Korea: an Initial Evaluation

Son UH, Dinzouna-Boutamba SD, Lee S, Yun HS, Kim JY, Joo SY, Jeong S, Rhee MH, Hong Y, Chung DI, Kwak D, Goo YK

Variant surface antigens (VSAs) encoded by pir families are considered to be the key proteins used by many Plasmodium spp. to escape the host immune system by antigenic variation. This...
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Inhibitory effect of red ginseng acidic polysaccharide from Korean red ginseng on phagocytic activity and intracellular replication of Brucella abortus in RAW 264.7 cells

Bernardo Reyes AW, Simborio H, Hop HT, Arayan LT, Min WG, Lee HJ, Rhee MH, Chang HH, Kim S

Korean red ginseng (KRG) has long been used in traditional Korean and Oriental medicine. However, the anti-bacterial mechanism and therapeutic efficiency of KGR for intracellular Brucella infection are still unclear....
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Distribution of Antibodies Specific to the 19-kDa and 33-kDa Fragments of Plasmodium vivax Merozoite Surface Protein 1 in Two Pathogenic Strains Infecting Korean Vivax Malaria Patients

Dinzouna-Boutamba SD, Lee S, Son UH, Song SM, Yun HS, Joo SY, Kwak D, Rhee MH, Chung DI, Hong Y, Goo YK

Objectives Plasmodium vivax merozoite surface protein 1 (PvMSP1) is the most intensively studied malaria vaccine candidate. Although high antibody response-inducing two C-terminal fragments of PvMSP1 (PvMSP1-19 and PvMSP1-42) are currently being...
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Water soluble tomato concentrate regulates platelet function via the mitogen-activated protein kinase pathway

Jeong D, Irfan M, Saba E, Kim SD, Kim SH, Rhee MH

Tomato extract has been shown to exert antiplatelet activity in vitro and to change platelet function ex vivo, but with limitations. In this study, antiplatelet activity of water soluble tomato...
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Synergistic Anti-bacterial Effects of Phellinus baumii Ethyl Acetate Extracts and beta-Lactam Antimicrobial Agents Against Methicillin-Resistant Staphylococcus aureus

Hong SB, Rhee MH, Yun BS, Lim YH, Song HG, Shin KS

BACKGROUND: The development of new drugs or alternative therapies effective against methicillin-resistant Staphylococcus aureus (MRSA) is of great importance, and various natural anti-MRSA products are good candidates for combination therapies....
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Anti-thrombotic activity of fermented rice bran extract with several oriental plants in vitro and in vivo

Jeon BR, Ji HD, Kim SJ, Lee CH, Kim TW, Rhee MH

Although the effects of the rice bran have recently been investigated, there is no information regarding platelet physiology available. However, it is well known that fermented natural plants have a...
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Acetyl Eburicoic Acid from Laetiporus sulphureus var. miniatus Suppresses Inflammation in Murine Macrophage RAW 264.7 Cells

Saba E, Son Y, Jeon BR, Kim SE, Lee IK, Yun BS, Rhee MH

The basidiomycete Laetiporus sulphureus var. miniatus belongs to the Aphyllophorales, Polyporaceae, and grows on the needleleaf tree. The fruiting bodies of Laetiporus species are known to produce N-methylated tyramine derivatives,...
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Study for the Sensitization Rate of Garlic and Onion Using Multiple Allergen Simultaneous Test-Immunoblot Assay

Kim JW, Rhee MH, Gang JS, Bang HH, Park JS, Jo KI, Choi YJ, Hwangbo Y

OBJECTIVE: Onion and garlic are a commonly consumed food in the Korean population. But these food materials have rarely been studied for their allergenic potentials. We analyzed the sensitization rate...
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Perilla oil improves blood flow through inhibition of platelet aggregation and thrombus formation

Jang JY, Kim TS, Cai J, Kim J, Kim Y, Shin K, Kim KS, Lee SP, Kang MH, Choi EK, Rhee MH, Kim YB

  • KMID: 2312116
  • Lab Anim Res.
  • 2014 Mar;30(1):21-27.
The inhibitory effects of perilla oil on the platelet aggregation in vitro and thrombosis in vivo were investigated in comparison with aspirin, a well-known blood flow enhancer. Rabbit platelet-rich plasma...
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Nattokinase improves blood flow by inhibiting platelet aggregation and thrombus formation

Jang JY, Kim TS, Cai J, Kim J, Kim Y, Shin K, Kim KS, Park SK, Lee SP, Choi EK, Rhee MH, Kim YB

The effects of nattokinase on the in vitro platelet aggregation and in vivo thrombosis were investigated in comparison with aspirin. Rabbit platelet-rich plasma was incubated with nattokinase and aggregation inducers...
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Inhibitory Effects of Epigallocatechin-3-Gallate on Microsomal Cyclooxygenase-1 Activity in Platelets

Lee DH, Kim YJ, Kim HH, Cho HJ, Ryu JH, Rhee MH, Park HJ

  • KMID: 2170686
  • Biomol Ther.
  • 2013 Jan;21(1):54-59.
In this study, we investigated the effect of (-)-epigallocatechin-3-gallate (EGCG), a major component of green tea catechins from green tea leaves, on activities of cyclooxygenase (COX)-1 and thromboxane synthase (TXAS),...
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Protective effects of recombinant Brucella abortus Omp28 against infection with a virulent strain of Brucella abortus 544 in mice

Lim JJ, Kim DH, Lee JJ, Kim DG, Min W, Lee HJ, Rhee MH, Kim S

The outer membrane proteins (OMPs) of Brucella (B.) abortus have been extensively studied, but their immunogenicity and protective ability against B. abortus infection are still unclear. In the present study,...
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