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Clinical Characteristics and Long-term Prognosis of Elderly-Onset Ulcerative Colitis in a Population-Based Cohort in the SongpaKangdong District of Seoul, Korea

Park SH, Jeong SK, Lee JH, Rhee KH, Kim YH, Hong SN, Kim KH, Seo SI, Cha JM, Park SY, Park H, Kim JS, Im JP, Yoon H, Kim SH, Jang J, Kim JH, Suh SO, Kim YK, Ye BD, Yang SK, Songpa-Kangdong Inflammatory Bowel Disease (SK-IBD) Study Group

Background/Aims: We aimed to evaluate the clinical characteristics and long-term prognosis of elderly-onset ulcerative colitis (EOUC) in Korean patients over a 30-year period using a wellestablished population-based cohort in the...
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Changing prevalence of Helicobacter pylori infection in children and adolescents

Park JS, Jun JS, Seo JH, Youn HS, Rhee KH

Helicobacter pylori infection has declined over recent decades. However, its prevalence remains high, and nearly 50% of the global population has been infected. In Korea, seroprevalence has steadily decreased in...
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Changes in Seroprevalence of Helicobacter pylori Infection over 20 Years in Jinju, Korea, from Newborns to the Elderly

Park JS, Jun JS, Ryu EY, Yeom JS, Park ES, Seo JH, Lim JY, Park CH, Woo HO, Baik SC, Lee WK, Cho MJ, Rhee KH, Youn HS

Background: The objective of this study was to examine changes in the prevalence of cytotoxic-associated gene A (CagA) positive Helicobacter pylori infection in Jinju, Korea, over the last 20 years. Methods:...
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Changes in the Treatment Strategies for Helicobacter pylori Infection in Children and Adolescents in Korea

Jun JS, Seo JH, Park JS, Rhee KH, Youn HS

The policies developed for the treatment of Helicobacter pylori infection in adults may not be the most suitable ones to treat children and adolescents. Methods used to treat children and...
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Diagnosis of Helicobacter pylori Infection in Children and Adolescents in Korea

Seo JH, Park JS, Rhee KH, Youn HS

Helicobacter pylori plays an important role in the pathogenesis of chronic gastritis, peptic ulcer disease, gastric cancer, and gastric mucosa-associated lymphoid tissue lymphoma. In Korea, the guidelines for the diagnosis...
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Helicobacter pylori Antigens Inducing Early Immune Response in Infants

Seo JH, Youn JH, Kim EA, Jun JS, Park JS, Yeom JS, Lim JY, Woo HO, Youn HS, Ko GH, Park JS, Baik SC, Lee WK, Cho MJ, Rhee KH

To identify the Helicobacter pylori antigens operating during early infection in sera from infected infants using proteomics and immunoblot analysis. Two-dimensional (2D) large and small gel electrophoresis was performed using...
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Anti-tumor Activity of Saussurea laniceps against Pancreas Adenocarcinoma

Lee KH, Kim BS, Rhee KH

The purpose of this study was to confirm the anti-tumor activity of an ethanol extract of Saussurea laniceps against pancreatic tumor and to isolate the active compound from S.laniceps extract....
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Correlations between the CagA Antigen and Serum Levels of Anti-Helicobacter pylori IgG and IgA in Children

Seo JH, Lim CW, Park JS, Yeom JS, Lim JY, Jun JS, Woo HO, Youn HS, Baik SC, Lee WK, Cho MJ, Rhee KH

We tested correlations between anti-Helicobacter pylori IgG and IgA levels and the urease test, anti-CagA protein antibody, degree of gastritis, and age. In total, 509 children (0-15 years) were enrolled....
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Association between Gastric pH and Helicobacter pylori Infection in Children

Seo JH, Park HK, Park JS, Yeom JS, Lim JY, Park CH, Woo HO, Youn HS, Jun JS, Ko GH, Baik SC, Lee WK, Cho MJ, Rhee KH

PURPOSE: To assess gastric pH and its relationship with urease-test positivity and histological findings in children with Helicobacter pylori infection. METHODS: Fasting gastric juices and endoscopic antral biopsy specimens were collected...
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Helicobacter pylori Infection and Intestinal Metaplasia among Healthy Adolescents

Park JS, Rhie K, Seo JH, Ryu EY, Kim HJ, Kim HJ, Lim JY, Woo HO, Baik SC, Lee WK, Cho MJ, Rhee KH, Ko GH, Youn HS

BACKGROUND/AIMS: The purpose of our study was to investigate the change in incidence of intestinal metaplasia (IM) in healthy, young adults over 10 years. MATERIALS AND METHODS: Urease test and histopathology...
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Proteome Analysis of a Catalase-deficient Isogenic Mutant of Helicobacter pylori 26695

Kang HL, Lee SG, Park JS, Song JY, Cho MJ, Baik SC, Youn HS, Seo JH, Rhee KH, Lee WK

Helicobacter pylori, a gram-negative bacterium, is a causative agent of gastroduodenal diseases of human. Human immune system produces harmful reactive oxygen species to kill this bacterium that locates the microaerophilic...
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Antibiotics resistance of Helicobacter pylori and treatment modalities in children with H. pylori infection

Seo JH, Woo HO, Youn HS, Rhee KH

Pediatric infection with Helicobacter pylori may occur early in childhood and persist lifelong. Global pediatric clinical studies have reported a decreasing tendency in the overall rate of H. pylori eradication....
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Helicobacter pylori: Bacterial Strategy for Incipient Stage and Persistent Colonization in Human Gastric Niches

Rhee KH, Park JS, Cho MJ

Helicobacter pylori (H. pylori) undergoes decades long colonization of the gastric mucosa of half the population in the world to produce acute and chronic gastritis at the beginning of infection,...
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Correlation between Positive Rate and Number of Biopsy Samples on Urease Test in Childhood Helicobacter pylori Infection

Seo JH, Park JS, Yeom JS, Lim JY, Park CH, Woo HO, Baik SC, Lee WK, Cho MJ, Rhee KH, Youn HS

To identify the correlation between the number of gastric biopsy samples and the positive rate, we compared the results of urease test using one and three biopsy samples from each...
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Development of an ELISA for Quantitative Detection of Immunoglobulin G (IgG) and IgA Antibodies to Helicobacter pylori for Use in Korean Patients with H. pylori-Associated Diseases

Seo JH, Jun JS, Youn HS, Yeom JS, Park JS, Park CH, Woo HO, Lee WK, Cho MJ, Rhee KH

  • KMID: 1806642
  • Gut Liver.
  • 2013 Jul;7(4):437-442.
BACKGROUND/AIMS: We aimed to develop a quantitative enzyme-linked immunosorbent assay (ELISA) using whole-cell lysates of Helicobacter pylori 51 and to investigate its validity. METHODS: Data from 300 plates were obtained by...
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Helicobacter pylori Infection and Duodenal Gastric Metaplasia in Healthy Young Adults

Seo JH, Do HJ, Park CH, Woo HO, Youn HS, Ko GH, Baik SC, Lee WK, Cho MJ, Rhee KH, Lee JH

BACKGROUND/AIMS: Duodenal ulcers occur relatively frequently in adolescents, like in adults, and may relate to Helicobacter pylori infection and duodenal gastric metaplasia (DGM). This study investigated the association between H....
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Influencing Factors to Results of the Urease Test: Age, Sampling Site, Histopathologic Findings, and Density of Helicobacter pylori

Seo JH, Youn HS, Park JJ, Yeom JS, Park JS, Jun JS, Lim JY, Park CH, Woo HO, Ko GH, Baik SC, Lee WK, Cho MJ, Rhee KH

PURPOSE: We investigated the positivity rate and the time period to the positive color change of the urease test in children and adults and assessed the correlation of the urease...
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Comparison of Gene Expression Patterns between Helicobacter pylor 26695 and its Superoxide Dismutase Isogenic Mutant

Cho MJ, Lee SG, Lee KH, Song JY, Lee WK, Baik SC, Rhee KH, Youn HS, Seo JH, Kang HL

Helicobacter pylori, a causative agent of gastroduodenal diseases, is a Gram-negative microaerophilic bacterium. Although H. pylori locates in the microaerophilic mucous layer, the bacteria would come into contact harmful reactive...
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Gastric Autoantigenic Proteins in Helicobacter Pylori Infection

Park JS, Lee SJ, Kim TH, Yeom J, Park ES, Seo JH, Jun JS, Lim JY, Park CH, Woo HO, Youn HS, Ko GH, Kang HL, Baik SC, Lee WK, Cho MJ, Rhee KH

PURPOSE: This study tried to identify novel gastric autoimmune antigens that might be involved in aggravating the atrophic gastritis among patients with Helicobacter pylori infection using two-dimensional immunoblotting analysis. MATERIALS AND...
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Changes in Anti-Group A Rotavirus Antibody Seroprevalence and Levels in the Western Gyeongnam Province of Korea Over 16 Years

Seo JH, Park JJ, Lim JY, Jun JS, Park CH, Woo HO, Youn HS, Kwon YC, Kang HL, Baik SC, Lee WK, Cho MJ, Rhee KH, Kim W

To observe how anti-group A rotavirus antibody seropositivity rates and levels have changed in the western region of Gyeongnam Province, 2,030 serum samples collected at four collection periods (1989-1990, 1994-1995,...
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