- Inhibitor of DNA-binding 4 contributes to the maintenance and expansion of cancer stem cells in 4T1 mouse mammary cancer cell line
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Park SJ, Kim RJ, Nam JS
- KMID: 1444966
- Lab Anim Res.
- 2011 Dec;27(4):333-338.
- doi: 10.5625/lar.2011.27.4.333
The cancer stem cell (CSC) hypothesis proposes that CSCs are the root of cancer. CSC-targeted therapies may prevent cancer relapse and provide more effective treatment. The expression of aldehyde dehydrogenase... -
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- Low Retinal Dehydrogenase 1 (RALDH1) Level in Prepubertal Boys with Autism Spectrum Disorder: A Possible Link to Dopamine Dysfunction?
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Pavăl D, Rad F, Rusu R, Niculae AS, Colosi HA, Dobrescu I, Dronca E
- KMID: 2388268
- Clin Psychopharmacol Neurosci.
- 2017 Aug;15(3):229-236.
- doi: 10.9758/cpn.2017.15.3.229
OBJECTIVE: Retinal dehydrogenase 1 (RALDH1) is a cytosolic enzyme which acts both as a source of retinoic acid (RA) and as a detoxification enzyme. RALDH1 has key functions in the... -
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- OCT4 Expression Enhances Features of Cancer Stem Cells in a Mouse Model of Breast Cancer
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Kim RJ, Nam JS
- KMID: 2053664
- Lab Anim Res.
- 2011 Jun;27(2):147-152.
- doi: 10.5625/lar.2011.27.2.147
The cancer stem cell (CSC) hypothesis proposes that CSCs are responsible for metastasis and disease recurrence. Therefore, targeting CSCs has the potential to significantly improve outcomes for cancer patients. The... -
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