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We investigated the patterns of degenerative changes of indoleamine-accumulating
cells (IACs) induced by 5,7-dihydroxytryptamine (5,7-DHT, 100 microg), and the
glial reaction to the neurodegenerative changes of IACs in the...
PURPOSE: Demonstrate unequivocally the generation of nitric oxide in experimental autoimmune uveoretinitis by electron spin resonance spectroscopy (ESR) using ferrous iron complex of N-methyl-D-glucamine dithiocarbamate, (MGD)2-Fe2+, as a spin...
PURPOSE: To investigate the relationship between vascular endothelial growth factor (VEGF) and the cancer stem cell-vascular niche complex in human retinoblastoma tissue.
METHODS: Six human retinoblastoma specimens primarily enucleated for...
In this study, we investigated whether retinal soluble proteins, such as
S-antigen, play a role in the induction of nitric oxide by macrophages in vitro.
Cells from the murine macrophage...
Exposure to light can induce photoreceptor cell death and exacerbate retinal degeneration. In this study, mice with genetic knockout of several genes, including rhodopsin kinase (Rhok-/-), arrestin (Sag-/-), transducin (Gnat1-/-),...