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Dronedarone hydrochloride enhances the bioactivity of endothelial progenitor cells via regulation of the AKT signaling pathway

Zhang J, Van Le TH, Rethineswaran VK, Kim YJ, Jang WB, Ji ST, Giang Ly TT, Ha JS, Yun J, Cheong JH, Jung J, Kwon SM

Cardiovascular disease (CVD) and its complications are the leading cause of morbidity and mortality in the world. Because of the side effects and incomplete recovery from current therapy, stem cell...
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Engineered M13 Peptide Carrier Promotes Angiogenic Potential of Patient-Derived Human Cardiac Progenitor Cells and In Vivo Engraftment

Jang WB, Ji ST, Park JH, Kim YJ, Kang S, Kim DY, Lee NK, Kim JS, Lim HJ, Choi J, Le THV, Ly TTG, Rethineswaran VK, Kim DH, Ha JS, Yun J, Baek SH, Kwon SM

BACKGROUND: Despite promising advances in stem cell-based therapy, the treatment of ischemic cardiovascular diseases remains a big challenge due to both the insufficient in vivo viability of transplanted cells and...
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