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A Study of Respiratory Syncytial Virus Outbreak at Postpartum Care Center in Busan, Korea

Hwang SJ, Yun HC, Ku PT, Sim JH, Lee MO

Respiratory syncytial virus (RSV) is common cause of acute respiratory infection in infants and young children. Group life in postpartum care centers is easily exposed to infectious diseases in neonates...
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Association between Serum Hyponatremia and Severity of Respiratory Symptoms in Infants with Respiratory Syncytial Virus Infection

Yum SO, Kim HH, Kim JK

Purpose: Association between hyponatremia and the severity of respiratory symptoms in infants with respiratory syncytial virus (RSV) infection has not yet been studied. This study aimed to compare respiratory symptoms,...
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Positive association of breastfeeding on respiratory syncytial virus infection in hospitalized infants: a multicenter retrospective study

Jang MJ, Kim YJ, Hong S, Na J, Hwang JH, Shin SM, Ahn YM

Background: Breastfeeding reportedly reduces the overall frequency of infections. Respiratory syncytial virus (RSV), the most common respiratory pathogen in infants, involves recurrent wheezing and has a pathogenic mechanism related to...
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Circulating Respiratory Syncytial Virus Genotypes and Genetic Variability of the G Gene during 2017 and 2018/2019 Seasonal Epidemics Isolated from Children with Lower Respiratory Tract Infections in Daejeon, Korea

Kang HM, Park KC, Park J, Kil HR, Yang EA

Background: Respiratory syncytial virus (RSV) is a major pathogen causing respiratory tract infections in infants and young children. The aim of this study was to confirm the genetic evolution of...
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Natural Killer and CD8 T Cells Contribute to Protection by Formalin Inactivated Respiratory Syncytial Virus Vaccination under a CD4-Deficient Condition

Ko EJ, Lee Y, Lee YT, Hwang HS, Park Y, Kim KH, Kang SM

Respiratory syncytial virus (RSV) causes severe pulmonary disease in infants, young children, and the elderly. Formalin inactivated RSV (FI-RSV) vaccine trials failed due to vaccine enhanced respiratory disease, but the...
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Analysis of factors affecting clinical feature and disease severity according to the subtypes of respiratory syncytial virus

Wi PH, Kim HS, Jung JA

Purpose: Respiratory syncytial virus (RSV) is one of the most common causes of respiratory tract infections, especially in patients aged < 3 years. There are 2 antigenically different RSV subtypes,...
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Single or Dual Infection with Respiratory Syncytial Virus and Human Rhinovirus: Epidemiology and Clinical Characteristics in Hospitalized Children in a Rural Area of South Korea

Kwon Y, Cho WJ, Kim HM, Lee J

PURPOSE: Respiratory syncytial virus (RSV) and human rhinovirus (hRV) are the most common causes of child respiratory viral infections. We aimed to investigate epidemiological and clinical characteristics of RSV and...
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Respiratory syncytial virus-associated seizures in Korean children, 2011–2016

Cha T, Choi YJ, Oh JW, Kim CR, Park DW, Seol IJ, Moon JH

PURPOSE: Respiratory syncytial virus (RSV) infection can cause various neurological complications. This study aimed to investigate the RSV-associated neurologic manifestations that present with seizures. METHODS: We retrospectively reviewed the medical records...
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Comparison of clinical severity between single- and coinfections of respiratory syncytial virus and influenza virus with common respiratory viruses

Park JS, Chu SY, Shin YY, Ryu IK, Tang CL, Choi J, Kim HB, Kim CK

PURPOSE: Multiple virus infections may affect clinical severity. We investigated the effect of coinfection of respiratory syncytial virus (RSV) and influenza virus with other respiratory viruses on clinical severity. METHODS: Data...
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Respiratory syncytial virus increases eosinophil extracellular traps in a murine model of asthma

Silveira J, Antunes GL, Gassen RB, Breda RV, Stein RT, Pitrez PM, da Cunha A

BACKGROUND: Respiratory viral infections are the leading cause of asthma exacerbations. Eosinophil activation results in the formation of eosinophil extracellular traps (EETs), which release web-like structures of DNA and proteins...
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Vaccine containing G protein fragment and recombinant baculovirus expressing M2 protein induces protective immunity to respiratory syncytial virus

Jo YM, Kim J, Chang J

PURPOSE: Respiratory syncytial virus (RSV) can cause serious respiratory illnesses such as pneumonia, asthma, and bronchiolitis in infants and elderly or immunocompromised individuals. An RSV vaccine has yet to be...
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Correlation of respiratory syncytial virus infection with climate parameters and air pollution levels in Korean children during 2005–2012

Jung JH, Chu SY, Kim JY, Han TH, Park SH, Chung JY, Kim HB

PURPOSE: Respiratory syncytial virus (RSV) is the major cause of acute lower respiratory tract infection (LRTI) in infants and children. We investigated the association of meteorological conditions and air pollution...
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Novel Cell Permeable Peptide Based on Multi Basic Furin-dependent Cleavage Site of Respiratory Syncytial Virus Fusion Protein

Cho J, Yi H, Lee MS, Lee CH, Kang C, Kim K

Cell permeable peptide (CPP) is able to transport itself or conjugated molecules such as nucleotides, peptides, and proteins into cells. Since short peptide of human immunodeficiency virus-1 Tat has been...
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Clinical characteristics and genetic variation in respiratory syncytial virus isolated from infants hospitalized due to acute bronchiolitis in Korea during winter season 2016–2017

Yon DK, Min CY, Ha EK, Jee HM, Jung YH, Lee KS, Sheen YH, Han MY

PURPOSE: Circulating patterns of predominant respiratory syncytial virus (RSV) genotypes in the community may be helpful in understanding molecular epidemiology and predicting future outbreaks of the RSV genotype. We investigated...
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Clinical Features of Respiratory Syncytial Virus Infection in Neonates: A Single Center Study

Chang SH, Jang GC, Yoon SW

PURPOSE: The aim of this study was to investigate the clinical characteristics of Respiratory syncytial virus (RSV) infection during the neonatal period to provide information that is useful in clinical...
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Bronchiolitis severity according to the infected viruses

Lee SJ, Park SK, Kim JH, Cho SM

PURPOSE: The aim of this study was to evaluate the severity of disease in children with acute bronchiolitis according to the type of infected virus. METHODS: From November 2007 to May...
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Comparison of cytokine expression profiles in infants with a rhinovirus induced lower respiratory tract infection with or without wheezing: a comparison with respiratory syncytial virus

Roh DE, Park SH, Choi HJ, Kim YH

PURPOSE: The aim of this study was to evaluate whether infants with rhinovirus (RV) infection-induced wheezing and those with respiratory syncytial virus (RSV) infection-induced wheezing have different cytokine profiles in...
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Lower Respiratory Tract Diseases Caused by Common Respiratory Viruses among Stem Cell Transplantation Recipients: A Single Center Experience in Korea

Hong KW, Choi SM, Lee DG, Cho SY, Lee HJ, Choi JK, Kim SH, Park SH, Choi JH, Yoo JH, Lee JW

PURPOSE: To describe the incidence, clinical courses, and risk factors for mortality of lower respiratory tract diseases (LRDs) caused by common respiratory viruses (CRVs) in stem cell transplantation (SCT) recipients. MATERIALS...
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Respiratory Syncytial Virus Infection Complicated by Extrapulmonary Manifestations

Jung JH, Kim YK, Choi HJ

Respiratory syncytial virus (RSV) typically causes lower respiratory tract infections in children, and most patients recover successfully. However, some infants and young children can have a severe course of disease...
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Comparison of nasal cytokine profiles of human metapneumovirus and respiratory syncytial virus

Park JS, Kim YH, Kwon E, Callaway Z, Fujisawa T, Kim CK

BACKGROUND: Human metapneumovirus (hMPV) and respiratory syncytial virus (RSV) share some epidemiological and clinical characteristics; however, few studies have examined the mechanisms by which these viruses induce airway inflammation. OBJECTIVE: This...
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