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Proposal of conditional random inter-stimulus interval method for unconstrained enclosure based GPIAS measurement systems

Choe Y, Park I

Gap prepulse inhibition of acoustic startle (GPIAS) method has been used effectively for the objective assessment of tinnitus in animals. Among two types of enclosures for the GPIAS, the unconstrained...
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A Study of Abnormal Reflexes in the Cerebral Palsied Patients

Lee BI, Jahng JS, Shin JS, Hong MK

Early diagnosis of persistent abnormal reflexes may be of great significance to a more effective functioning of the cerebral palsied child. It is important to know the normal and abnormal...
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An Infantile Case of Sandhoff Disease Presenting With Swallowing Difficulty

Moon JG, Shin MA, Pyo H, Choi SU, Kim HK

Infants with Sandhoff disease typically appear normal until 3–6 months of age. As the disease progresses, they present with symptoms such as loss of motor skills, exaggerated startle response to...
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Familiar Hyperekplexia, a Potential Cause of Cautious Gait: A New Korean Case and a Systematic Review of Phenotypes

Lee Y, Kim NY, Hong S, Chung SJ, Jeong SH, Lee PH, Sohn YH

Familial hyperekplexia, also called startle disease, is a rare neurological disorder characterized by excessive startle responses to noise or touch. It can be associated with serious injury from frequent falls,...
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Clinical Study of the pathologic Reflexes in Cerebral Palsy

Lee BI, Jahng JS, Kim JW

The relative incidence of cerebral palsy has increased recently over that of poliomyelitis, due to the improvement in the social, medical, and economic status of our country. It is important...
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Memantine Attenuates Salicylate-induced Tinnitus Possibly by Reducing NR2B Expression in Auditory Cortex of Rat

Jang CH, Lee S, Park IY, Song A, Moon C, Cho GW

Memantine, a noncompetitive antagonist of the N-methyl-d-aspartate (NMDA) receptor, suppresses the release of excessive levels of glutamate that may induce neuronal excitation. Here we investigated the effects of memantine on...
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Effects of 5HT1A Activation on Gating Profile Following 5HT Depletion in Rats Lacking Social Attachment Since Weanling

Tai YM, Ko CY, Lin CC, Wan YY, Chung JY, Liu YP

OBJECTIVE: Central 5-HT1A receptor is involved in the modulation of sensorimotor gating function. However, its precise role is not clearly defined in developmentally social deprived (isolation rearing, IR) rats featured...
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