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Influence of Reduced Folate Carrier and Dihydrofolate Reductase Genes on Methotrexate-Induced Cytotoxicity

Yoon SA, Choi JR, Kim JO, Shin JY, Zhang X, Kang JH

  • KMID: 2270806
  • Cancer Res Treat.
  • 2010 Sep;42(3):163-171.
PURPOSE: The aim of this study is to investigate the effect of genetic variations and the expression of the reduced folate carrier (RFC) and dihydrofolate reductase (DHFR) on the drug...
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