- Amelioration of DSS-Induced Acute Colitis in Mice by Recombinant Monomeric Human Interleukin-22
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Kim S, Hong EH, Lee CK, Ryu Y, Jeong H, Heo S, Lee JJ, Ko HJ
- KMID: 2536253
- Immune Netw.
- 2022 Jun;22(3):e26.
- doi: 10.4110/in.2022.22.e26
IL-22, a pleiotropic cytokine, is known to have a profound effect on the regeneration of damaged intestinal barriers. The tissue-protective properties of IL-22 are expected to be potentially exploited in... -
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- A combined application of molecular docking technology and indirect ELISA for the serodiagnosis of bovine tuberculosis
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Song S, Zhang Q, Yang H, Guo J, Xu M, Yang N, Yi J, Wang Z, Chen C
- KMID: 2530443
- J Vet Sci.
- 2022 May;23(3):e50.
- doi: 10.4142/jvs.21270
Background: There is an urgent need to find reliable and rapid bovine tuberculosis (bTB) diagnostics in response to the rising prevalence of bTB worldwide. Toll-like receptor 2 (TLR2) recognizes components... -
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- Recombinant anti-D for prevention of maternal-foetal Rh(D) alloimmunization: a randomized multi-centre clinical trial
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Mayekar RV, Paradkar G, Bhosale AA, Sachan R, Beeram S, Anand AR, Mundle SR, Trivedi Y, R, Patole KP, Sambarey P, Daftary GV, John J, Divekar GH
- KMID: 2500421
- Obstet Gynecol Sci.
- 2020 Apr;63(3):315-322.
- doi: 10.5468/ogs.2020.63.3.315
Objective To compare the efficacy and safety of recombinant anti-D (R-anti-D) with conventional polyclonal anti-D (Poly anti-D) in preventing maternal-fetal rhesus D (RhD) alloimmunization and to investigate the immunogenicity of R-anti-D. Methods This was... -
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- Detection of Autoantibodies Against Nucleoporin p62 in Sera of Patients With Primary Biliary Cholangitis
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Bauer A, Habior A
- KMID: 2431607
- Ann Lab Med.
- 2019 May;39(3):291-298.
- doi: 10.3343/alm.2019.39.3.291
BACKGROUND: Primary biliary cholangitis (PBC) is an autoimmune liver disease characterized by specific autoantibodies. We evaluated the prevalence of autoantibodies against nucleoporin p62 (anti-p62) in PBC patients' sera to determine... -
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- Immune Response of BALB/c Mice toward Putative Calcium Transporter Recombinant Protein of Trichomonas vaginalis
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Mendoza-Oliveros T, Arana-Argáez V, Alvaréz-Sánchez LC, Lara-Riegos J, Alvaréz-Sánchez ME, Torres-Romero JC
- KMID: 2441604
- Korean J Parasitol.
- 2019 Feb;57(1):33-38.
- doi: 10.3347/kjp.2019.57.1.33
Trichomoniasis is a common sexually transmitted infection caused by Trichomonas vaginalis, which actually does not exist a vaccine for control or prevention. Thus, the identification of new and potent immunogens... -
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- Spheroid Culture of Mammalian Olfactory Receptor Neurons: Potential Applications for a Bioelectronic Nose
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Kim S, Kim SY, Choi SK, Bae J, Jeon WB, Jang JE, Moon C
- KMID: 2430113
- Exp Neurobiol.
- 2018 Dec;27(6):574-592.
- doi: 10.5607/en.2018.27.6.574
The olfactory system can detect many odorants with high sensitivity and selectivity based on the expression of nearly a thousand types of olfactory receptors (ORs) in olfactory receptor neurons (ORNs).... -
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- L1 Recombinant Proteins of HPV Tested for Antibody Forming Using Sera of HPV Quadrivalent Vaccine
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Akuzum B, Kim S, Nguyen TT, Hong J, Lee S, Kim E, Kim J, Choi Y, Jhun H, Lee Y, Kim H, Sohn DH, Kim S
- KMID: 2414555
- Immune Netw.
- 2018 Jun;18(3):e19.
- doi: 10.4110/in.2018.18.e19
Virus-like particles (VLPs) derived from human papillomavirus (HPV) L1 capsid proteins were used for HPV quadrivalent recombinant vaccine. The HPV quadrivalent vaccine is administrated in a 3-dose regimen of initial... -
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- Species Specific Antiviral Activity of Porcine Interferon-α8 (IFNα8)
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Kim E, Jhun H, Kim J, Park U, Jo S, Kwak A, Kim S, Nguyen TT, Kang Y, Choi I, Lee J, Kim H, Kim Y, Lee S, Kim S
- KMID: 2400628
- Immune Netw.
- 2017 Dec;17(6):424-436.
- doi: 10.4110/in.2017.17.6.424
Interferons (IFNs) have been known as antiviral genes and they are classified by type 1, type 2, and type 3 IFN. The type 1 IFN consists of IFNα, IFNβ, IFNτ,... -
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- Recombinant Activated Factor VII as a Second Line Treatment for Postpartum Hemorrhage
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Park SC, Yeom SR, Han SK, Jo YM, Kim HB
- KMID: 2405119
- Korean J Crit Care Med.
- 2017 Nov;32(4):333-339.
- doi: 10.4266/kjccm.2016.00787
BACKGROUND: Severe or massive postpartum hemorrhage (PPH) has remained a leading cause of maternal mortality for decades across the world and it results in critical obstetric complications. Recombinant activated factor... -
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- Characterization of Echinostoma cinetorchis endoribonuclease, RNase H
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Lim SB, Cha SH, Jegal S, Jun H, Park SH, Jeon BY, Pak JH, Bakh YY, Kim TS, Lee HW
- KMID: 2389984
- Korean J Parasitol.
- 2017 Aug;55(4):451-455.
- doi: 10.3347/kjp.2017.55.4.451
Echinostoma cinetorchis is an oriental intestinal fluke causing significant pathological damage to the small intestine. The aim of this study was to determine a full-length cDNA sequence of E. cinetorchis... -
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- Production of Recombinant Anti-Cancer Vaccines in Plants
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Lee JH, Ko K
- KMID: 2386899
- Biomol Ther.
- 2017 Jul;25(4):345-353.
- doi: 10.4062/biomolther.2016.126
Plant expression systems have been developed to produce anti-cancer vaccines. Plants have several advantages as bioreactors for the production of subunit vaccines: they are considered safe, and may be used... -
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- Molecular cloning, purification and immunogenicity of recombinant Brucella abortus 544 malate dehydrogenase protein
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Reyes AW, Simborio H, Hop HT, Arayan LT, Kim S
- KMID: 2363344
- J Vet Sci.
- 2016 Mar;17(1):119-122.
- doi: 10.4142/jvs.2016.17.1.119
The Brucella mdh gene was successfully cloned and expressed in E. coli. The purified recombinant malate dehydrogenase protein (rMDH) was reactive to Brucella-positive bovine serum in the early stage, but... -
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Cloning, Expression, and Purification of Hyperthermophile α-Amylase from
Pyrococcus woesei -
Ghasemi A, Ghafourian S, Vafaei S, Mohebi R, Farzi M, Taherikalani M, Sadeghifard N
- KMID: 2518227
- Osong Public Health Res Perspect.
- 2015 Dec;6(6):336-340.
- doi: 10.1016/j.phrp.2015.10.003
Objectives In an attempt α-amylase gene from Pyrococcus woesei was amplified and cloned into a pTYB2 vector to generate the recombinant plasmid pTY- α-amylase. Methods Escherichia coli BL21 used as a host and... -
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- Expression of human norovirus VP1 gene and VP1-specific monoclonal antibodies
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Kim JW, Kong YJ, Kim MS, Lee HJ, Lee SW, Kang SY
- KMID: 2169096
- J Biomed Res.
- 2015 Sep;16(3):109-114.
- doi: 10.12729/jbr.2015.16.3.109
Norovirus (NoV) is an etiologic agent of human and animal acute gastroenteritis and is a member of the family Caliciviridae. NoV is classified based on nucleotide sequences of the VP1... -
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- Protein Expression of the Bombyx mori Decapentaplegic Gene using the Baculovirus Expression Vector System
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Jeong ST, Park SW
- KMID: 2068741
- J Bacteriol Virol.
- 2015 Sep;45(3):256-261.
- doi: 10.4167/jbv.2015.45.3.256
The Bombyx mori decapentaplegic gene is one of the conserved genes in vertebrate and invertebrates. The TGF-beta superfamily contains conserved polypeptide growth factors that play important roles in different cellular... -
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- Identification of Immunodominant B-cell Epitope Regions of Reticulocyte Binding Proteins in Plasmodium vivax by Protein Microarray Based Immunoscreening
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Han JH, Li J, Wang B, Lee SK, Nyunt MH, Na S, Park JH, Han ET
- KMID: 2381757
- Korean J Parasitol.
- 2015 Aug;53(4):403-411.
- doi: 10.3347/kjp.2015.53.4.403
Plasmodium falciparum can invade all stages of red blood cells, while Plasmodium vivax can invade only reticulocytes. Although many P. vivax proteins have been discovered, their functions are largely unknown.... -
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- Seroreactive Mycobacterial Proteins and Lipid in Cattle with Bovine Tuberculosis
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Jeon HS, Shin AR, Son YJ, Kim JM, Jang Y, Kim S, Lee KI, Choi CH, Park JK, Kim HJ
- KMID: 2149211
- J Bacteriol Virol.
- 2015 Jun;45(2):112-125.
- doi: 10.4167/jbv.2015.45.2.112
Bovine tuberculosis caused by Mycobacterium bovis is a major economic problem in several countries. Antibody responses are useful indicators of M. bovis infection of cattle. To overcome drawback of serological... -
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- Usefulness of nBos d 4, 5 and nBos d 8 Specific IgE Antibodies in Cow's Milk Allergic Children
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Cingolani , Di Pillo S, Cerasa M, Rapino D, Consilvio , Attanasi M, Scaparrotta A, Marcovecchio ML, Mohn A, Chiarelli
- KMID: 2260255
- Allergy Asthma Immunol Res.
- 2014 Mar;6(2):121-125.
- doi: 10.4168/aair.2014.6.2.121
PURPOSE: The aim of study was to assess the value of recombinants in predicting the degree of symptoms in children with and without anaphylaxis to cow's milk. METHODS: The study included... -
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- Non-chromatographic Method for the Hepatitis B Virus X Protein Using Elastin-Like Polypeptide Fusion Protein
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Kwon SH, Cho H
- KMID: 2518025
- Osong Public Health Res Perspect.
- 2012 Jun;3(2):79-84.
- doi: 10.1016/j.phrp.2012.04.003
Objectives Hepatitis B virus (HBV) is a member of the hepadnavirus family. The HBV genome contains four genes designated as S, C, P, and X. The HBV X (HBx) gene encodes... -
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- Mouse Dual Ig Domain Containing Cell Adhesion Molecule Protein Expression and Purification Using the Baculovirus Expression Vector System
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Park SW, Choi JH, Goo TW, Kim SR, Lee GG, Kang SW
- KMID: 2055049
- J Bacteriol Virol.
- 2010 Sep;40(3):123-130.
- doi: 10.4167/jbv.2010.40.3.123
A baculovirus expression vector system (BEVS) is used routinely to produce recombinant proteins in the milligram scale. Dual Ig domain containing cell adhesion molecule (DICAM) belongs to the type I... -
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