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Properties of GST-CALM expressed in E. coli

Kim JA, Kim SR, Jung YK, Woo SY, Seoh JY, Hong YS, Kim HL

  • KMID: 1109309
  • Exp Mol Med.
  • 2000 Jun;32(2):93-99.
Clathrin-coated vesicles (CCVs) are involved in protein and lipid trafficking between intracellular compartments in eukaryotic cells. CCVs are composed of clathrin and assembly proteins. The clathrin assembly protein lymphoid...
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Conjugation and deconjugation of ubiquitin regulating the destiny of proteins

Baek KH

  • KMID: 1088651
  • Exp Mol Med.
  • 2003 Feb;35(1):1-7.
The homeostasis for a number of cellular proteins is regulated by not only phosphorylation and dephosphorylation, but also ubiquitination and deubiquitination. A number of proteins involved in the degradation of...
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Production and characterization of monoclonal antibodies against amphiphysins

Jin YL, Kim KY, Soung NK, Shin EY, Kim EG, Kim SR

  • KMID: 1085742
  • Exp Mol Med.
  • 2001 Jun;33(2):69-75.
Amphiphysin I and II, proteins enriched in nerve terminals, form heterodimers and interact with dynamin and synaptojanin through their Src homology 3 (SH3) domain. In order to study the expression...
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Cell-type specific regulation of thrombospondin-1 expression and its promoter activity by regulatory agents

Kim SA, Kang JH, Cho IH, Bae SW, Hong KJ

  • KMID: 938874
  • Exp Mol Med.
  • 2001 Sep;33(3):117-123.
Thrombospondin-1 (TSP-1), a multifunctional protein that is able to function as a negative regulator of solid tumor progression and angiogenesis, is normally present at a very low level but rapidly...
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Phospholipase D is activated and phosphorylated by casein kinase-II in human U87 astroglioma cells

Ahn BH, Min G, Bae YS, Bae YS, Min DS

  • KMID: 1105277
  • Exp Mol Med.
  • 2006 Feb;38(1):55-62.
Elevated expression of protein casein kinase II (CKII) stimulated basal phospholipase D (PLD) activity as well as PMA-induced PLD activation in human U87 astroglioma cells. Moreover, CKII-selective inhibitor, emodin and...
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The homotrimeric structure of HtrA2 is indispensable for executing its serine protease activity

Nam MK, Seong YM, Park HJ, Choi JY, Kang S, Rhim H

  • KMID: 1105275
  • Exp Mol Med.
  • 2006 Feb;38(1):36-43.
Serine protease activity of high temperature requrement 2 (HtrA2) is essential for promoting cell death, as well as for protecting against cellular stresses. An X-ray crystallographic study described the formation...
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Diagnostic Value of a Chimeric TSH Receptor (Mc4)-Based Bioassay for Graves' Disease

Lee JI, Jang HW, Kim SK, Choi JY, Kim JY, Hur KY, Kim JH, Min YK, Chung JH, Kim SW

BACKGROUND/AIMS: Graves' disease (GD) is caused by thyroid-stimulating hormone receptor (TSHR) and thyroid-stimulating immunoglobulin (TSI). We used a recently introduced, technically enhanced TSI bioassay to assess its diagnostic value and...
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