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Distribution of Adenoviral Vector in Brain after Intravenous Administration

Jin JY, Moon CI, Moon CI, Kang WS, Jeong DC

The delivery of transgenes to the central nervous system (CNS) can be a valuable tool to treat CNS diseases. Various systems for the delivery to the CNS have been developed;...
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Prokaryotic expression and characterization of human AP DNA endonuclease

Oh SH, Song DW, Lee MY

The expression of major human apurinic/apyrimidinic DNA endonuclease (APEX) from its cDNA in E. coli (DH5 alpha) was attempted in order to obtain a biologically active recombinant APEX....
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Enhanced immune response with foot and mouth disease virus VP1 and interleukin-1 fusion genes

Park JH, Kim SJ, Oem JK, Lee KN, Kim YJ, Kye SJ, Park JY, Joo YS

The capsid of the foot and mouth disease (FMD) virus carries the epitopes that are critical for inducing the immune response. In an attempt to enhance the specific immune response,...
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Gene cloning of the human cytomegalovirus (HCMV) antigen reactive with the serum from a HCMV-infected patient

Kim MN, Park CG, Hwang ES, Lim DG, Park JW, Seoh JY, Kook YH, Lee HJ, Choi SB, Cha CY

The human cytomegalovirus(HCMV) gene encoding the protein reactive with the sera of HCMV-infected patient was cloned and characterized. A reactive phage clone was screened from a lambda gt11 expression library...
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Human Monoclonal Antibody Inhibiting Reverse Transcriptase Activity of Hepatitis B Virus Polymerase Protein

Park SJ, Seol SY, Jee SR, Park ET, Lee YJ, Lee SH, Chung JM, Cho HD, Jeong YJ, Choi IH, Park SG

  • KMID: 935184
  • Korean J Gastroenterol.
  • 2007 Feb;49(2):85-92.
BACKGROUND/AIMS: To develop a novel treatment method for hepatitis B virus (HBV) infection, we aimed to make a human monoclonal antibody inhibiting reverse transcriptase (RT) activity of P protein which...
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COMP-Angiopoietin-1 Promotes Cavernous Angiogenesis in a Type 2 Diabetic Rat Model

Kim SO, Lee HS, Ahn K, Park K

Cartilage oligomeric matrix protein-angiopoietin-1 (COMP-Ang1) is an angiogenic factor for vascular angiogenesis. The aim was to investigate the effect of an intracavernosal injection of COMP-Ang1 on cavernosal angiogenesis in a...
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