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Molecular Mechanism of GnRH Interaction with GnRH Receptor in an Evolutionary Viewpoint

Seong JY, Kwon HB

  • KMID: 1540203
  • J Korean Soc Endocrinol.
  • 2000 Dec;15(6):779-790.
No Abstract Available.
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Characteristics of Acromegalic Patients According to GH Pulse Frequency

Lee GC, Yang IM, Woo JT, Kim SW, Kim JW, Kim YS, Choi YK

  • KMID: 2080482
  • Korean J Med.
  • 1997 Apr;52(4):437-444.
OBJECTIVES: Pulsatile secretion of GH are present in acromegalics and normal men. GH concentration profiles in patients with acromegaly are characterized by rapid GH pulsatility and high interpulse concentrations. There...
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Detection of the Gonadotropin Releasing Hormone (GnRH) and Its Receptor in Cancer Cell HT-1197 and HT-1376, and Effect of GnRH on Cancer Cell Cycle

Baik SH, Kim MO, Bahk JY

  • KMID: 2292368
  • Korean J Urol.
  • 2001 Feb;42(2):172-179.
Gonadotropin releasing hormone (GnRH) is believed to be pivotal hormone in hypothalamo-pituitary gonadal axis and the hypothalamus is believed as the exclusive organ producing GnRH and pituitary is for GnRH...
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A Familial Case of Idiopathic Hypogonadotropic Hypogonadism Occurred in a Boy and His Sister

Yoo EJ, Kim KS, Kim YW, Yoo HW, Kim EY

  • KMID: 2193517
  • J Korean Soc Pediatr Endocrinol.
  • 2006 Dec;11(2):199-204.
Isolated gonadotropin deficiency can be idiopathic or a part of X-linked Kallmann syndrome associated with anosmia. There have been several trials to reveal the genetic mutations that affect gonadotropin secretion,...
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Gonadotropin Releasing Hormone (GnRH) and GnRH Receptor in Normal Bladder Epithelia and Their Role in Bladder Epithelial Proliferation

Kim MO, Lee JH, Park MS, Lee HL, Bahk JY

PURPOSE: To confirm the production of extra-hypothalamic gonadotropin releasing hormone (GnRH) and GnRH receptor in bladder mucosal epithelia, and a potential role of GnRH on the bladder, normal human bladder...
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Current medical treatment of uterine fibroids

Sohn GS, Cho S, Kim YM, Cho CH, Kim MR, Lee SR, for the Working Group of Society of Uterine Leiomyoma

Uterine fibroids (leiomyomas or myomas), benign monoclonal tumors, are the most common benign tumors in women. Heavy or prolonged menstrual bleeding, abnormal uterine bleeding, resultant anemia, pelvic pain, infertility, and/or...
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KAL Gene and GnRH Receptor Gene Analysis in Patients with Kallmann's Syndrome

Park KH, Mo HJ, Kim JY, Kim JY, Bae SW, Lee BS, Kim IK, Kim SK, Kim KA, Ahn YH

  • KMID: 2199559
  • J Korean Soc Endocrinol.
  • 1999 Dec;14(4):645-656.
BACKGROUND: Kallmann's syndrome is related to the defect in migration of olfactory neuron and GnRH neuron from the olfactory placode to the brain and it represents hypogonadism with anosmia or...
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Methylphenidate and Central Precocious Puberty: A Probable Side Effect among Seven Children with the Attention Deficit Hyperactivity Disorder

Ergür AT, Gül H, Gül A

Methylphenidate (MPH) is the most preferred drug for treatment of the attention deficit hyperactivity disorder (ADHD). Here, we aimed to discuss the possible effects and mechanisms of MPH on precocious...
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Expression of Gonadotropin-Releasing Hormone Receptor in Human Uterine Endometrial and Ovarian Tissues

Kim JW, Namkoong S

  • KMID: 1531927
  • J Korean Cancer Assoc.
  • 1997 Feb;29(1):117-127.
PURPOSE: Gonadotropin-releasing hormone (Gn-RH) can cause regression of hormonedependent human tumors, including uterine endometrial and ovarian carcinomas. These effects were thought to be mediated through the inhibition of gonadotropic and...
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Detection of the Expression of GnRH and GnRH Receptor mRNAs and Effect of GnRH on Prostate Cancer Cell Proliferation

Bahk JY, Hyun JS, Chang YW, Lee H, Choi BS, Lee KI, Baik HC, Hong JW, Oh JY

  • KMID: 2290106
  • Korean J Urol.
  • 1997 Sep;38(9):963-972.
Prostatic cancer is the typical hormone dependant cancer and several kinds of hormones are used for the treatment of prostate cancer. Since Harris had proposed the hypothalamo-pituitary gonadal axis, the...
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Effects of Toluene, Xylene and Trichloroethylene on the Regulation of GnRH, GnRH Receptor and Pit-1 Gene Expression in Male Rat Hypothalamus and Pituitary

Kim DH, Lee H, Lee CK, Kang DS, Kim JH, Lee JT, Chun JH, Lee CU, Ki NS

  • KMID: 2028022
  • Korean J Occup Environ Med.
  • 1998 May;10(2):267-281.
The workplace exposure of chemicals has steadily increased, therefore the concern for subsequent effect on reproductive outcome has been an important issue in occupational medicine. In previous studies, higher rates...
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Regulation of gonadotropin releasing hormone receptor mRNA expression in cultured rat granulosa cells

Park Y, Kam K, Cheon M, Ryu K

The homologous regulation of pituitary Gonadotropin Releasing Hormone Receptor (GnRH-R) mRNA expression by GnRH has been well demonstrated. However, the regulation of the ovarian GnRH-R is poorly...
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