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Levels of Soluble Interleukin-2 Receptors in Serum of Patients with Behçet's Disease

Hur W, Lee SH, Bang D, Lee S, Kim JC, Chung TH

BACKGROUND: Interleukin-2 receptor (IL-2) is expressed and released predominantly activated T lymphocyte. Increased serum levels of soluble IL-2R have been noted in a variety of autoimmune diseases and in conditions...
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Eosinophil Cationic Protein in HSP and in IgA Nephropathy

Namgoong M, Kim JS

  • KMID: 2254997
  • Korean J Nephrol.
  • 1997 Mar;16(1):21-27.
Interleukin-5 (IL-5), which is known to be an activator of human eosinophil, increases in IgA nephropathy. In order to find out the relationship between activated eosinophil function and the pathogenesis...
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Effect of polyadenylic.polyuridylic acid on cellular responses of peripheral blood mononuclear cells from patients with chronic active hepatitis B

Kim WH, Hahm KB, Park SJ, Kang JK, Park IS, Choi HJ, Shin JS, Youn JK

We have investigated in vitro proliferative responses of peripheral blood mononuclear cells and productions of interferon-gamma and soluble interleukin-2 receptors by these cells from 6 patients with chronic active hepatitis...
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A Study of EFFECT and MECHANISM of IL-2on SURVIVAL of EOSINOPHILS

Kim HS, Lee YM, Choi YS, Kim KH, Im GI, Jeong SW, Moon SH, Kim HT, Uh ST, Kim YH, Park CS

BACKGROUND: Interleukin-5 (IL-5) is responsible for eosinophilia in allergic diseases. In allergic bronchial asthma, there is a correlation between the extent of eosinophil infiltration in bronchial mucosa and IL-5 concentrations....
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Serum Interleukin-2, Soluble Interleukin-2 Receptors and Neopterin Concentrations in Guillain-Barre Syndrome

Lim JG, Park YC, Kim JC

  • KMID: 2342403
  • J Korean Neurol Assoc.
  • 1994 Jun;12(2):279-288.
Guillain-Barre syndrome (GBS) is an autoimmune disease with an acute evolution of inflammatory demyelinating polyradiculoneuropathy. Although the precise immune mechanisms and involved antigens are uncertain, both humoral and cellular immune...
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The Enhancing IL-2R alpha mRNA Expression induces A Marked T Cel Proliferation with Interleukin-2 and Anti-CD3 mAb

Kim HJ, Jo EK, Park JK, Kim JK

  • KMID: 1557250
  • Korean J Immunol.
  • 1998 Dec;20(4):427-434.
Culture of human peripheral T lymphocytes with irnmobilized anti-CD3 rnAb plus IL-2 resulted in a marked proliferation and the enhancing IL-2Ra mRNA expression. The process of the T cell activation...
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T Cell Activation in Ischemic Heart Disease

Hur SH, Kim KS, Han SW, Shin KM, Kim YN, Kim KB

BACKGROUND: It was recently shown that human atherosclerotic plaque contains large numbers of T lymphocytes : this indicates that immune and inflammatory mechanism may be important factors in the pathogenesis...
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Serum soluble IL-2 receptor levels following interferon and ribavirin combination therapy with chronic hepatitis C

Lee JY, Yang JW, Park SH, Park CJ, Seo JS, Lee JH, Kim YB, Kim HY, Yoo JY

  • KMID: 2306171
  • Korean J Med.
  • 2000 Nov;59(5):511-515.
BACKGROUND: To evaluate the cellular immune response to interferon(IFN)-alpha and ribavirin combination therapy in patients with chronic hepatitis C, we monitored serum levels of soluble IL-2 receptor(sIL2R) before and after...
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Peripheral Biomarkers for First-Episode Psychosis—Opportunities from the Neuroinflammatory Hypothesis of Schizophrenia

Trovão N, Prata J, VonDoellinger O, Santos S, Barbosa M, Coelho R

OBJECTIVE: Schizophrenia is a disabling disorder of unknown aetiology, lacking definite diagnostic method and cure. A reliable biological marker of schizophrenia is highly demanded, for which traceable immune mediators in...
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The Correlation between the Expression of CD99 and the Cell Cycle

Yu CS, Chang MC, Oh SK

  • KMID: 2145187
  • J Korean Surg Soc.
  • 2001 Oct;61(4):347-356.
PURPOSE: The cell cycle control system is necessary for the normal growth and differentiation of cells. The purposes of this study were to compare CD99 expression with a known...
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Effect of General Anesthesia with Isoflurane and Epidural Anesthesia Bupivacaine and Surgery on Interleukin-2 Receptor Levels

Choi YJ, Lee YC, Woo NS, Choi YS

Inability to synthetize adequate amounts of IL-2 has been suggested to be the basis of defective T-cell function following anesthesia with the operation. The present study was designed to examine...
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Analysis of the T Lymphocyte Subsets in the Peripheral Blood of Patients with Myasthenia Gravis

Choi C, Choi IH, Kim WK, Sunwoo IN

  • KMID: 1546751
  • J Korean Neurol Assoc.
  • 1998 Feb;16(1):49-54.
It is known that the activated peripheral T lymphocytes are increased in patients with autoimmune disorders such as systemic lupus erythematosis, rheumatoid arthritis, multiple sclerosis and autoimmune thyroiditis, but...
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Differences in immunophenotyping of mucosal lymphocytes between ulcerative colitis and Crohn's disease

Lee HB, Kim JH, Yim CY, Kim DG, Ahn DS

  • KMID: 1038877
  • Korean J Intern Med.
  • 1997 Jan;12(1):7-15.
OBJECTIVES: Immunologic studies have characterized the numbers and types of inflammatory cells in diseased inflammatory bowel disease (IBD) mucosa but have yielded conflicting results regarding intestinal lymphocytes activation in IBD. ...
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Detection of Interleukin 2 Receptor and EBV Antibody in Nasopharyngeal Carcinoma

Sun DI, Kim MS, Cho SH, Suh BD, Kim HK, Lee KS, Chung SM, Yoon SC

  • KMID: 2274290
  • Korean J Otolaryngol-Head Neck Surg.
  • 1997 Feb;40(2):175-184.
Nasopharyngeal carcinoma(NPC) is highly prevalent among southeastern Chinese,and not rare in Korea. Due to NPC usually spreads submucosally and complexity of anatomy in the nasopharynx, we have difficulty in determining...
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Genome-Wide Association Studies of Autoimmune Thyroid Diseases, Thyroid Function, and Thyroid Cancer

Hwangbo Y, Park YJ

Thyroid diseases, including autoimmune thyroid diseases and thyroid cancer, are known to have high heritability. Family and twin studies have indicated that genetics plays a major role in the development...
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The Clinical Significance of Serum CD23 and CD25 in Chronic Cough Patients

Choi JC, Park YB, Jee HS, Kim JY, Park IW, Choi BW, Hue SH

BACKGROUND: Cough Coughing is the most common complaint for which patients seek medical service. When cough sustains caughing continues over 3 weeks in non-smokers who do not take cough-provoking drugs, they...
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Serum Levels of Soluble CD30 in Childrens with Atopic Dermatitis

Kim SJ, Lee EH, Shim JY, Jung HL, Park MS, Keum DH

  • KMID: 2314253
  • Pediatr Allergy Respir Dis.
  • 2001 Dec;11(4):319-326.
PURPOSE: The pathogenesis of atopic dermatitis is not clearly defined yet, but the pathogenetic role of Th2 cells has been supposed. CD30 is a membrane-bound glycoprotein that may be expressed...
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Immunologic Changes of Peripheral Blood Lymphocytes in Kawasaki Disease after Intravenous Gamma Globulin Therapy

Shim JY, Kim KM, Kim YH, Hong SJ

  • KMID: 1747691
  • J Korean Pediatr Soc.
  • 1996 May;39(5):712-721.
PURPOSE: Kawasaki disease(KD) is multi-systemic vasculitis and coronary artery abnormalities can develop up to 30 percent in untreated patients. Several observations suggest that immune activation and the secretion of cytokines...
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In vivo ligation of glucocorticoid-induced TNF receptor enhances the T-cell immunity to herpes simplex virus type 1

La S, Kim E, Kwon B

  • KMID: 1056231
  • Exp Mol Med.
  • 2005 Jun;37(3):193-198.
GITR (glucocorticoid-induced TNF receptor) is a recently identified member of the TNF receptor superfamily. The receptor is preferentially expressed on CD4+CD25+ regulatory T cells and GITR signals break the suppressive...
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Clinical and Immunologic Features of Miliary Tuberculosis withPositive Bone Marrow Study

Song KS, Yong SJ, Shin KC, Lee WY, Ryu JS

  • KMID: 2317969
  • Tuberc Respir Dis.
  • 1996 Feb;43(1):22-29.
BACKGROUND: Abnormalities of the peripheral blood are frequent and varied in patients with miliary tuberculosis. Anemia,leukopenia, thrombocytopenia, pancytopenia, monocytosis, basophilia, eosinophilia and leukemoid reactions have been reported. These abnormalities are...
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