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Effect of Sildenafil on Neuropathic Pain and Hemodynamics in Rats

Huang LJ, Yoon MH, Choi JI, Kim WM, Lee HG, Kim YO

PURPOSE: The inhibition of phosphodiesterase 5 produces an antinociception through the increase of cyclic guanosine monophosphate (cGMP), and increasing cGMP levels enhance the release of gamma-aminobutyric acid (GABA). Furthermore, this...
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