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GABA Receptors Genes Polymorphisms and Alcohol Dependence: No Evidence of an Association in an Italian Male Population

Terranova , Tucci M, Di Pietra , Ferrara SD

  • KMID: 2279946
  • Clin Psychopharmacol Neurosci.
  • 2014 Aug;12(2):142-148.
OBJECTIVE: The genes encoding for gamma-aminobutyric acid (GABA) A and B receptors may be considered as candidates for alcoholism; genetic alterations at this level may produce structural and functional diversity...
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A Role of Glutamate and GABA Receptors in the Generation of Formalin-induced Impulse Firing of Spinal Dorsal Horn Neurons in the Rat

Bae JY, Jang JH, Jeon YH, Yoon DM, Leem JW, Nam TS, Paik KS

  • KMID: 2199679
  • J Korean Pain Soc.
  • 2003 Dec;16(2):118-132.
BACKGROUND: A peripheral subcutaneous injection of formalin produces biphasic impulse firing of the spinal nociceptive neurons. The roles of excitatory glutamatergic and inhibitory GABAergic receptors were investigated in the formalin-induced...
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Role of gamma-aminobutyric acid B (GABA B) receptors in the regulation of kainic acid-induced cell death in mouse hippocampus

Lee HK, Seo YJ, Choi SS, Kwon MS, Shim EJ, Lee JY, Suh HW

  • KMID: 1116198
  • Exp Mol Med.
  • 2005 Dec;37(6):533-545.
Kainic acid (KA) is well-known as an excitatory, neurotoxic substance. In mice, KA administered intracerebroventricularly (i.c.v.) lead to morphological damage of hippocampus expecially concentrated on the CA3 pyramidal neurons. In...
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Effect of Sildenafil on Neuropathic Pain and Hemodynamics in Rats

Huang LJ, Yoon MH, Choi JI, Kim WM, Lee HG, Kim YO

PURPOSE: The inhibition of phosphodiesterase 5 produces an antinociception through the increase of cyclic guanosine monophosphate (cGMP), and increasing cGMP levels enhance the release of gamma-aminobutyric acid (GABA). Furthermore, this...
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