- Estrogen modulates transactivations of SXR-mediated liver X receptor response element and CAR-mediated phenobarbital response element in HepG2 cells
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Min G
- KMID: 994396
- Exp Mol Med.
- 2010 Nov;42(11):731-738.
- doi: 10.3858/emm.2010.42.11.074
The nuclear receptors, steroid and xenobiotic receptor (SXR) and constitutive androstane receptor (CAR) play important functions in mediating lipid and drug metabolism in the liver. The present study demonstrates modulatory... -
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- Inhibition of acyl-coenzyme A:cholesterol acyltransferase stimulates cholesterol efflux from macrophages and stimulates farnesoid X receptor in hepatocytes
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An S, Jang YS, Park JS, Kwon BM, Paik YK, Jeong TS
- KMID: 1094120
- Exp Mol Med.
- 2008 Aug;40(4):407-417.
- doi: 10.3858/emm.2008.40.4.407
We investigated the mechanism of spontaneous cholesterol efflux induced by acyl-coenzyme A:cholesterol acyltransferase (ACAT) inhibition, and how an alteration of cholesterol metabolism in macrophages impacts on that in HepG2 cells.... -
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